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固体脂质纳米粒在药物递送中的几种应用

Several Applications of Solid Lipid Nanoparticles in Drug Delivery.

作者信息

Khil Noor Hassan Sulaiman, Sharma Shaweta, Sharma Pramod Kumar, Alam Aftab

机构信息

Department of Pharmacy, School of Medical & Allied Sciences, Greater Noida, Uttar Pradesh, India.

出版信息

Curr Mol Med. 2024;24(9):1077-1090. doi: 10.2174/1566524023666230720110351.

Abstract

Rapid progress is being made in the area of nanotechnology; solid lipid nanoparticles are currently at the forefront of research and development. They have the capability of becoming employed in an extensive number of applications, including the delivery of medications, clinical treatment, and research, in addition to uses in other areas of academic inquiry that could benefit from their utilisation. This article presents a thorough analysis of solid lipid nanoparticles, covering subjects such as their goals, preparation strategy, applications, advantages, and possible remedies for the issues that have been raised. This review provides a discussion of solid lipids that is both in-depth and comprehensive. Studies that investigate the manner in which SLNs are prepared and the routes via which they are administered are typical. Aspects concerning the route of administration of SLNs as well as the destiny of the carriers in vivo are also investigated in this paper.

摘要

纳米技术领域正在取得快速进展;固体脂质纳米粒目前处于研发前沿。它们有能力应用于大量领域,包括药物递送、临床治疗和研究,此外还可用于其他能从其应用中受益的学术研究领域。本文对固体脂质纳米粒进行了全面分析,涵盖其目标、制备策略、应用、优势以及针对所提出问题的可能解决方法。本综述对固体脂质进行了深入且全面的讨论。研究固体脂质纳米粒的制备方式及其给药途径是常见的。本文还研究了固体脂质纳米粒的给药途径以及载体在体内的命运等方面。

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