Ramaswamy Krithika A, Shetty Shivaprasad, Shetty Prashanth
Department of Yoga, SDM College of Naturopathy and Yogic Sciences, Ujire, Karnataka, India.
SDM College of Naturopathy and Yogic Sciences, Ujire, Karnataka, India.
Front Neurol. 2023 Jul 5;14:1197026. doi: 10.3389/fneur.2023.1197026. eCollection 2023.
Migraine is a complex neurological disorder that typically presents with unilateral cephalgia associated with cognitive impairment and reduced interoception. These symptoms result in socio-economic repercussions due to reduced productivity, efficiency, and work performance. Therefore, along with headache management, improving cognition and interoception should also be significant therapeutic targets to effectively manage migraine. To achieve this, we propose to explore the role of a yoga-based visual respiratory biofeedback (VRB) as a possible therapeutic strategy.
At least 64 participants will be recruited for the trial after screening for eligibility criteria, using the migraine screening questionnaire and Montreal cognitive assessment test. They will be randomly allocated (1:1) to either the experimental group receiving a 20-min session of yoga-based VRB or the control group who will be asked to watch a documentary film for the same duration. Visuospatial cognition will be assessed by the Corsi block-tapping task, and cardiac interoceptive accuracy will be assessed by the heartbeat counting task at baseline and immediately after the intervention. Based on the distribution and variance of the data obtained, analysis will be conducted based on linear mixed models using SPSS version 28.0.1.0, with a two-sided -value of < 0.05 considered to be statistically significant.
To the best of our knowledge, this is the first study to design and assess the effects of yoga-based biofeedback therapy on cognition and cardiac interoception in migraineurs. Furthermore, we postulated that pranayama's therapeutic effects might be enhanced by using visual yogic respiratory biofeedback. Considering the socio-economic burden of migraine, if found effective, VRB investigated in the trial could be considered as a therapeutic strategy.
ClinicalTrials.gov CTRI, CTRI/2023/03/050430.
偏头痛是一种复杂的神经系统疾病，通常表现为单侧头痛，并伴有认知障碍和内感受功能减退。这些症状会导致社会经济影响，因为生产力、效率和工作表现都会下降。因此，除了头痛管理外，改善认知和内感受功能也应成为有效管理偏头痛的重要治疗目标。为实现这一目标，我们建议探索基于瑜伽的视觉呼吸生物反馈（VRB）作为一种可能的治疗策略。
使用偏头痛筛查问卷和蒙特利尔认知评估测试对至少64名参与者进行资格标准筛查后，将他们招募到试验中。他们将被随机分配（1:1）到接受20分钟基于瑜伽的VRB训练的实验组或被要求观看相同时长纪录片的对照组。视觉空间认知将通过Corsi方块敲击任务进行评估，心脏内感受准确性将在基线和干预后立即通过心跳计数任务进行评估。根据所获得数据的分布和方差，使用SPSS 28.0.1.0版本基于线性混合模型进行分析，双侧p值<0.05被认为具有统计学意义。
据我们所知，这是第一项设计并评估基于瑜伽的生物反馈疗法对偏头痛患者认知和心脏内感受功能影响的研究。此外，我们推测通过使用视觉瑜伽呼吸生物反馈可能会增强调息法的治疗效果。考虑到偏头痛的社会经济负担，如果发现有效，试验中研究的VRB可被视为一种治疗策略。
ClinicalTrials.gov CTRI，CTRI/2023/03/050430。
