一种由访谈者进行单项评分的简单方法可预测 15 年内的痴呆发生情况。

A Simple Single Item Rated by an Interviewer Predicts Incident Dementia Over 15 Years.

机构信息

Florida State University College of Medicine, Tallahassee, FL, USA.

University of Geneva, Geneva, Switzerland.

出版信息

J Alzheimers Dis. 2023;95(1):69-74. doi: 10.3233/JAD-230417.

DOI:10.3233/JAD-230417

PMID:37483005

Abstract

Subjective memory is useful to detect cognitive deficits not apparent on objective tests. This research evaluates whether memory rated by an interviewer predicts incident dementia. Health and Retirement Study participants without cognitive impairment at baseline whose memory was rated by the interviewer were analyzed (N = 12,749). Worse interviewer-rated memory was associated with higher risk of incident dementia over 15 years (HR = 1.40, 95% CI = 1.27-1.54). The association was evident even among participants in the top quartile of objective memory performance (HR = 1.71, 95% CI = 1.26-2.32). Interviewer-rated memory may be a low-cost supplement to neuropsychological evaluation to predict dementia risk beyond self-reports and objective cognitive testing.

摘要

主观记忆有助于发现客观测试中不明显的认知缺陷。本研究评估了由访谈者评估的记忆是否可以预测痴呆症的发生。分析了基线时没有认知障碍且记忆力由访谈者评估的健康与退休研究参与者（N=12749）。在 15 年内，访谈者评估的记忆较差与痴呆症发生的风险较高相关（HR=1.40，95%CI=1.27-1.54）。即使在客观记忆表现处于前四分之一的参与者中，这种关联也很明显（HR=1.71，95%CI=1.26-2.32）。与自我报告和客观认知测试相比，访谈者评估的记忆可能是神经心理评估的低成本补充，可以预测痴呆症风险。