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霍奇金-赫胥黎模型与弗兰肯豪泽-赫胥黎模型在听神经电刺激中的应用研究

A study of the application of the Hodgkin-Huxley and the Frankenhaeuser-Huxley model for electrostimulation of the acoustic nerve.

作者信息

Motz H, Rattay F

出版信息

Neuroscience. 1986 Jul;18(3):699-712. doi: 10.1016/0306-4522(86)90064-3.

Abstract

By means of electrostimulation of the acoustic nerve profoundly deaf patients can, in the best cases, reach almost complete speech understanding without lip reading. In this paper the information content of the signals supplied to patients is examined by a study of action potential generation by means of the Hodgkin-Huxley and the Frankenhaeuser-Huxley equations solved by means of a digitally controlled analogue computer. The response to sinusoidal signals and to signals with the wave shape of certain vowels is investigated and compared with results from animal experiments and observation on patients.

摘要

通过对听神经进行电刺激,深度失聪患者在最佳情况下能够几乎完全理解言语,而无需唇读。本文通过使用由数字控制模拟计算机求解的霍奇金-赫胥黎方程和弗兰肯豪泽-赫胥黎方程来研究动作电位的产生,从而检验提供给患者的信号的信息内容。研究了对正弦信号以及具有某些元音波形的信号的响应,并与动物实验结果和对患者的观察结果进行了比较。

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