Yin Zhaoyin, Ouyang Yuhui, Dang Bing, Zhang Luo
Institute of Urban Meteorology, China Meteorological Administration, Beijing, China.
Beijing Meteorological Service Center, Beijing, China.
Clin Transl Allergy. 2023 Jul;13(7):e12280. doi: 10.1002/clt2.12280.
Artemisia pollen is the most prevalent outdoor aeroallergen causing respiratory allergies in Beijing, China. Pollen allergen concentrations have a direct impact on the quality of life of those suffering from allergies. Artemisia pollen deposition grading predictions can provide early warning for the protection and treatment of patients as well as provide a scientific basis for allergen specific clinical immunotherapy.
To develop a model of Artemisia pollen grading to predict development in patients with pollen allergy.
Artemisia pollen data from four pollen monitoring stations in Beijing as well as the number of Artemisia pollen allergen serum specific immunoglobulin E positive cases in Beijing Tongren Hospital from 2014 to 2016 were used to develop a statistical model of pollen deposition and provide optimised threshold values.
A logarithmic correlation existed between the number of patients with Artemisia pollen allergy and Artemisia pollen deposition, and the average pollen deposition for three consecutive days was most correlated with the number of allergic patients. Based on the threshold of the number of patients and the characteristics of Artemisia pollen, a five-stage pollen deposition grading model was developed to predict the degree of pollen allergy.
Graded prediction of pollen deposition may help pollen allergic populations benefit from preventive interventions before onset.
在中国北京,蒿属花粉是导致呼吸道过敏的最常见的室外气传过敏原。花粉过敏原浓度直接影响过敏患者的生活质量。蒿属花粉沉降分级预测可为患者的防护与治疗提供预警,也可为过敏原特异性临床免疫治疗提供科学依据。
建立蒿属花粉分级模型以预测花粉过敏患者的病情发展。
利用北京四个花粉监测站的蒿属花粉数据以及2014年至2016年北京同仁医院蒿属花粉过敏原血清特异性免疫球蛋白E阳性病例数,建立花粉沉降统计模型并提供优化阈值。
蒿属花粉过敏患者数量与蒿属花粉沉降之间存在对数相关性,连续三天的平均花粉沉降与过敏患者数量相关性最高。基于患者数量阈值和蒿属花粉特征,建立了一个五阶段花粉沉降分级模型以预测花粉过敏程度。
花粉沉降分级预测可能有助于花粉过敏人群在发病前从预防性干预中获益。