库欣综合征——短暂的免疫缺陷状态？
Cushing's syndrome--transitory immune deficiency state?
作者信息
Würzburger M I, Prelević G M, Brkić S D, Vucković S, Pendić B
出版信息
Postgrad Med J. 1986 Jul;62(729):657-9. doi: 10.1136/pgmj.62.729.657.
Abstract
A 28 year old female patient with Cushing's syndrome due to an adrenal adenoma also suffered from recurrent urinary infections (proteus), tonsillitis (streptococcus), permanent candidiasis and perimandibular abscess (Staphylococcus pyogenes). Suppression of cellular and humoral immunity was confirmed by in vitro tests. After successful right adrenalectomy the clinical signs of Cushing's syndrome disappeared and no evidence of either bacterial or fungal infection were noted one year postoperatively. Immunological tests showed the restitution of both cellular and humoral immunity. The course of the disease in the patient supports the idea that Cushing's syndrome might be considered as a transitory immune deficiency state.
摘要
一名28岁因肾上腺腺瘤导致库欣综合征的女性患者还反复发生泌尿系统感染（变形杆菌）、扁桃体炎（链球菌）、慢性念珠菌病和下颌周脓肿（化脓性葡萄球菌）。体外试验证实细胞免疫和体液免疫受到抑制。右肾上腺切除成功后，库欣综合征的临床症状消失，术后一年未发现细菌或真菌感染迹象。免疫测试显示细胞免疫和体液免疫均恢复。该患者的病程支持这样一种观点，即库欣综合征可被视为一种暂时性免疫缺陷状态。
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