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压力可导致冠心病的机制。

Mechanisms by which stress can lead to coronary heart disease.

作者信息

Henry J P

出版信息

Postgrad Med J. 1986 Jul;62(729):687-93. doi: 10.1136/pgmj.62.729.687.

Abstract

Much stress is of psychological origin and due to emotional arousal. The mechanisms by which anger, helplessness, or a sense of control and serenity exert their various neuroendocrine effects are discussed. Primacy is given to three systems; to the catecholamines, to testosterone and to cortisol. Evidence that they interact to accelerate the arteriosclerotic process is cited. The protective aspects of intimacy are discussed together with evidence that certain personality types promote it in the marital situation while others do not. It is suggested that the post-traumatic stress syndrome may relate to the coronary-prone personality for it involves an alexithymic disturbance of the emotional competence required for successful intimacy.

摘要

许多压力源于心理因素和情绪唤起。本文讨论了愤怒、无助感或控制感与平静感产生各种神经内分泌效应的机制。重点关注三个系统:儿茶酚胺、睾酮和皮质醇。文中引用了它们相互作用加速动脉硬化进程的证据。探讨了亲密关系的保护作用,以及某些人格类型在婚姻关系中促进亲密关系而其他人格类型则不然的证据。研究表明,创伤后应激障碍可能与易患冠心病的人格有关,因为它涉及成功建立亲密关系所需的情感能力的述情障碍。

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