Liu Quanxi, Zhu Yan, Wang Wei, Dong Yongli
Quanxi Liu, Beijing Hospital of Integrated Traditional Chinese and Western Medicine, Hospital of Integrated Traditional Chinese and Western Medicine, Beijing University of Chinese Medicine, Department of Digestive, Beijing 100039, China.
Yan Zhu, Beijing Hospital of Integrated Traditional Chinese and Western Medicine, Hospital of Integrated Traditional Chinese and Western Medicine, Beijing University of Chinese Medicine, Department of Digestive, Beijing 100039, China.
Pak J Med Sci. 2023 Jul-Aug;39(4):1013-1017. doi: 10.12669/pjms.39.4.6994.
To investigate the clinical efficacy of cognitive behavioral therapy combined with pinaverium bromide tablets in admitted patients with irritable bowel syndrome (IBS).
This is a retrospective study. A total of 60 patients with IBS admitted to Beijing Hospital of Integrated Traditional Chinese and Western Medicine between June 2021 and June 2022 were selected and randomly divided into two groups. Patients in the control group were treated with pinaverium bromide tablets, and those in the observation group were treated with cognitive behavior therapy combined with pinaverium bromide tablets. The improvement of clinical symptoms and quality of life before and after treatment was compared for the two groups, IBS-SSS scale and IBS-QOL scale were used to compare the improvement of clinical symptoms and quality of life between the two groups of patients before and after treatment. SAS score and SDS score were used to evaluate the psychology of the two groups. Adverse reactions occurring during the treatment were recorded, such as nausea and vomiting, dizziness and headache, etc.
The efficacy of the observation group was higher than that of the control group and the difference was significant (P<0.05). After treatment, the IBS-SSS score in the observation group and the control group decreased and the IBS-QOL score increased. The SDS score and SAS score in the observation group were better than those in the control group (P< 0.05). After treatment, there was no significant difference in adverse reactions between the observation group and the control group (P > 0.05).
Cognitive behavioral therapy combined with pinaverium bromide tablets is significantly effective in the treatment of patients with IBS, which can effectively relieve symptoms such as diarrhea and abdominal pain, and reduce irritable bowel reactions.
探讨认知行为疗法联合匹维溴铵片治疗收治的肠易激综合征（IBS）患者的临床疗效。
本研究为回顾性研究。选取2021年6月至2022年6月在北京中西医结合医院收治的60例IBS患者，随机分为两组。对照组患者采用匹维溴铵片治疗，观察组患者采用认知行为疗法联合匹维溴铵片治疗。比较两组治疗前后临床症状及生活质量的改善情况，采用IBS-SSS量表和IBS-QOL量表比较两组患者治疗前后临床症状及生活质量的改善情况。采用SAS评分和SDS评分评估两组患者的心理状态。记录治疗期间出现的不良反应，如恶心呕吐、头晕头痛等。
观察组疗效高于对照组，差异有统计学意义（P<0.05）。治疗后，观察组和对照组的IBS-SSS评分均降低，IBS-QOL评分均升高。观察组的SDS评分和SAS评分均优于对照组（P<0.05）。治疗后，观察组与对照组不良反应发生率比较，差异无统计学意义（P>0.05）。
认知行为疗法联合匹维溴铵片治疗IBS患者疗效显著，可有效缓解腹泻、腹痛等症状，减少肠道应激反应。
