Department of Rheumatology, Guanghua Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai, China,
Department of Rheumatology, Guanghua Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai, China.
Dermatology. 2020;236(2):170-178. doi: 10.1159/000498848. Epub 2019 Aug 21.
This study aimed to compare the Hospital Anxiety and Depression Scale (HADS) and the Zung Self-Rating Anxiety/Depression Scale (SAS/SDS) in evaluating anxiety and depression in psoriatic arthritis (PsA) patients.
A total of 70 PsA patients were enrolled. Demographic and clinical characteristics were collected after enrollment. HADS-A and SAS were used to evaluate the anxiety of PsA patients, while HADS-D and SDS were used to evaluate the depression of PsA patients.
Similar results were observed in detecting the rate of anxiety by HADS-A and SAS (27.1 vs. 21.4%, p = 0.424), and there was no difference in classifying the severity of anxiety by HADS-A and SAS (p = 0.347). The Spearman test also disclosed that HADS-A score was positively associated with SAS score (p <0.001). The rates of depression were similar by HADS-D and SDS (27.1 vs. 40.0%; p = 0.108). However, different results were observed in grading the severity of anxiety by HADS-D and SDS (p = 0.009), and no correlation was observed between HADS-D and SDS scores (p = 0.138). The consumption of time for HADS assessment was shorter than that for SAS/SDS assessment (p < 0.001). In addition, a positive correlation of HADS-A score with patients' global assessment (PGA) (p = 0.022) and fatigue scores (p = 0.028) was discovered, and HADS-D score was positively associated with PGA score (p = 0.019). SAS or SDS score presented less correlation with clinical features of PsA patients, which illuminated that only SAS score was positively associated with duration of psoriasis (p = 0.030).
HADS seems to be a better option for anxiety and depression assessment than SAS/SDS in PsA patients.
本研究旨在比较医院焦虑抑郁量表(HADS)和zung 自评焦虑/抑郁量表(SAS/SDS)在评估银屑病关节炎(PsA)患者焦虑和抑郁中的作用。
共纳入 70 例 PsA 患者。入组后收集患者的人口统计学和临床特征。HADS-A 和 SAS 用于评估 PsA 患者的焦虑,HADS-D 和 SDS 用于评估 PsA 患者的抑郁。
HADS-A 和 SAS 检测焦虑发生率的结果相似(27.1% vs. 21.4%,p=0.424),HADS-A 和 SAS 对焦虑严重程度的分级无差异(p=0.347)。Spearman 检验也显示 HADS-A 评分与 SAS 评分呈正相关(p<0.001)。HADS-D 和 SDS 评估的抑郁发生率相似(27.1% vs. 40.0%,p=0.108)。但 HADS-D 和 SDS 对抑郁严重程度的分级不同(p=0.009),HADS-D 和 SDS 评分之间无相关性(p=0.138)。HADS 评估耗时短于 SAS/SDS 评估(p<0.001)。此外,HADS-A 评分与患者整体评估(PGA)(p=0.022)和疲劳评分(p=0.028)呈正相关,HADS-D 评分与 PGA 评分呈正相关(p=0.019)。SAS 或 SDS 评分与 PsA 患者的临床特征相关性较低,表明仅 SAS 评分与银屑病持续时间呈正相关(p=0.030)。
在 PsA 患者中,HADS 似乎是评估焦虑和抑郁的更好选择,优于 SAS/SDS。