Bellucci S
Phlebologie. 1986 Apr-Jun;39(2):459-63.
In the course of disseminated lupus erythematosus (DLE), the development of arterial or venous thrombosis is sometimes observed. They are rare in the course of hematological forms of DLE, in which the more or less constant leucopenia is accompanied to variable extent by the affection of the other blood-lines: thrombocytopenia and/or thrombocytopathy and/or hemolytic anemia. The discovery of a circulating anticoagulant seems to be correlated with the existence of thrombosis. In fact it involves antiphospholipid antibodies, responsible for the protraction of certain coagulation tests, which shows up their existence. Recent studies have shown recognition of the membrane phospholipids of the vascular endothelial cell. A functional imbalance in this would be observed to encourage the synthesis of factors favorable to thrombosis.
在播散性红斑狼疮（DLE）病程中，有时会观察到动脉或静脉血栓形成。在血液学形式的DLE病程中它们较为罕见，在这种情况下，或多或少持续存在的白细胞减少症会在不同程度上伴有其他血细胞系的受累：血小板减少和/或血小板病和/或溶血性贫血。循环抗凝剂的发现似乎与血栓形成的存在相关。事实上，它涉及抗磷脂抗体，这些抗体导致某些凝血试验延长，从而显示出它们的存在。最近的研究表明血管内皮细胞膜磷脂的识别。观察到其中的功能失衡会促进有利于血栓形成的因子的合成。
