Rokkas T, Anggiansah A, Uzoechina E, Owen W J, Sladen G E
Scand J Gastroenterol. 1986 Jun;21(5):614-20. doi: 10.3109/00365528609003108.
We studied 20 patients with typical symptoms of gastro-oesophageal reflux, to determine whether the diagnostic accuracy of 24-h pH monitoring might be retained in a test using a shorter time. The duration and number of reflux episodes were used to calculate a frequency and duration score (FDS) for the 24-h period, the daytime period, the nighttime period, a 3-h postprandial period after eating a test meal (provocation test), and a 21-h period that excluded this 3-h postprandial period. The daytime FDS was significantly higher than nighttime FDS (p less than 0.02), and there was good correlation between the 21-h FDS and the 3-h postprandial FDS (rs = 0.695; p less than 0.01). We conclude that the 3-h postprandial testing after a standard meal provocation test is a practical, accurate, and well-tolerated method of diagnosing gastro-oesophageal reflux. The results also demonstrated the relative importance of daytime as opposed to nocturnal reflux in producing symptoms and oesophagitis.
我们研究了20例有典型胃食管反流症状的患者，以确定在较短时间的检测中，24小时pH监测的诊断准确性是否能够保持。反流发作的持续时间和次数用于计算24小时时段、白天时段、夜间时段、进食试验餐（激发试验）后3小时餐后时段以及排除该3小时餐后时段的21小时时段的频率和持续时间评分（FDS）。白天的FDS显著高于夜间的FDS（p<0.02），并且21小时FDS与3小时餐后FDS之间存在良好的相关性（rs = 0.695；p<0.01）。我们得出结论，标准餐激发试验后3小时餐后检测是一种实用、准确且耐受性良好的诊断胃食管反流的方法。结果还表明，与夜间反流相比，白天反流在产生症状和食管炎方面相对更重要。
