食管测压与pH测试用于诊断胃食管反流的相关性
Correlation between manometric and pH tests for gastro-oesophageal reflux.
作者信息
Stanciu C, Hoare R C, Bennett J R
出版信息
Gut. 1977 Jul;18(7):536-40. doi: 10.1136/gut.18.7.536.
Abstract
A series of tests, including gastro-oesophageal sphincter pressure measurement, short-term pH tests, and 15-hour overnight oesophageal pH recording were applied to 42 normal subjects and 214 patients with typical reflux symptoms. The results were compared by multivariate discriminant analysis. Sphincter pressure measurements misclassified 32%, stressed provocative manoeuvres 14-5%, and the best single discriminator from the overnight pH study was time below pH 5, which misclassified 13%. However, a combination of the number of reflux episodes in 15 hours with their mean duration reduced misclassification to 8-8%. Using this function, a boundary between normal and reflux can be drawn, and the degree of abnormality can be expressed visually as well as numerically.
摘要
对42名正常受试者和214名有典型反流症状的患者进行了一系列测试，包括胃食管括约肌压力测量、短期pH测试以及15小时夜间食管pH记录。通过多变量判别分析对结果进行比较。括约肌压力测量的错误分类率为32%，应激激发动作的错误分类率为14.5%，夜间pH研究中最佳的单一判别指标是pH值低于5的时间，其错误分类率为13%。然而，将15小时内反流发作次数与其平均持续时间相结合可将错误分类率降至8.8%。利用这一函数，可以划分正常与反流的界限，异常程度可以通过视觉和数值方式表示出来。
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