健康人群的餐后胃食管反流
Postprandial gastro-oesophageal reflux in healthy people.
作者信息
Kaye M D
出版信息
Gut. 1977 Sep;18(9):709-12. doi: 10.1136/gut.18.9.709.
Abstract
Distal oesophageal pH was monitored for three hours after a standard meal in 10 young healthy subjects without symptoms of gastro-oesophageal reflux. Episodes of reflux occurred in nine of these subjects; and, in five, oesophageal pH was less than 5 for between 11 and 75% of the first postprandial hour. Intermittent incompetence of the lower oesophageal sphincter after food must, therefore, be regarded as a normal phenomenon. The method described would be suitable for the evaluation of agents believed to weaken or to strengthen the lower oesophageal sphincter.
摘要
在10名无胃食管反流症状的年轻健康受试者摄入标准餐后，监测其食管远端pH值3小时。其中9名受试者出现反流情况；5名受试者在餐后第1小时内，食管pH值有11%至75%的时间低于5。因此，进食后食管下括约肌间歇性功能不全应被视为一种正常现象。所描述的方法适用于评估被认为会削弱或增强食管下括约肌功能的药物。
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