Chopra A, Rana P V, Narayanaswamy A S, Bajpai C P, Madan V S
Trop Geogr Med. 1986 Sep;38(3):197-202.
A study of eleven patients presenting with neurological complications following acute viral conjunctivitis, mostly haemorrhagic, is reported and the literature reviewed. A Guillain-Barre syndrome-like profile was seen in six patients while the remaining had features of radiculomyelitis. Besides asymmetrical neurological deficits, protein cell reaction and residual muscle wasting, the occurrence of dysautonomias was the striking feature noted in the patients with a Guillain-Barre syndrome-like profile. The dysautonomic features included fatal paroxysmal hypertensive and hypotensive crises in one patient and self limiting tachycardias, episodic profuse sweating, abnormal expiration-inspiration ratio and valsalva ratio in four patients. High antibody titers to EV-70 virus were seen in five patients. A follow up of one and a half year revealed poor neurologic recovery in patients with radiculomyelitis as compared to good functional recovery in others. The importance of early recognition and appropriate treatment of dysautonomias is emphasised. The probable aetiopathogenesis of the neurological complications including dysautonomias is discussed.
本文报告了11例急性病毒性结膜炎后出现神经并发症（大多为出血性）患者的研究情况，并对相关文献进行了综述。6例患者表现出吉兰 - 巴雷综合征样特征，其余患者具有神经根脊髓炎的特征。除了不对称性神经功能缺损、蛋白细胞反应和残留肌肉萎缩外，自主神经功能障碍的发生是具有吉兰 - 巴雷综合征样特征患者的显著特点。自主神经功能障碍的特征包括1例患者出现致命性阵发性高血压和低血压危象，4例患者出现自限性心动过速、发作性大量出汗、异常的呼气 - 吸气比和瓦尔萨尔瓦动作比值。5例患者检测到针对EV - 70病毒的高抗体滴度。随访一年半发现，与其他患者良好的功能恢复相比，神经根脊髓炎患者的神经恢复较差。强调了早期识别和适当治疗自主神经功能障碍的重要性。文中还讨论了包括自主神经功能障碍在内的神经并发症可能的病因发病机制。
