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罗马尼亚市场销售的谷物产品中 A 型和 B 型单端孢霉烯族毒素的出现情况。

Occurrence of Types A and B Trichothecenes in Cereal Products Sold in Romanian Markets.

机构信息

Department of Animal Nutrition, Faculty of Veterinary Medicine, University of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca, 400372 Cluj-Napoca, Romania.

Department of Biomedical Sciences, Ross University School of Veterinary Medicine, Basseterre P.O. Box 334, Saint Kitts and Nevis.

出版信息

Toxins (Basel). 2023 Jul 20;15(7):466. doi: 10.3390/toxins15070466.

DOI:10.3390/toxins15070466
PMID:37505735
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10467109/
Abstract

In view of the frequent occurrences of mycotoxins in cereals, this study assessed the presence of trichothecenes in 121 samples from Romanian markets. These samples were divided into five groups based on product type: (1) bread and bakery products containing white flour, (2) half-brown bread with whole wheat flour, (3) brown bread containing rye flour, (4) pasta, and (5) raw wheat. Gas Chromatography-Mass Spectrometry was used to detect 13 different mycotoxins, which included the Type A compounds HT-2 toxin and T-2 toxin, as well as the Type B compounds deoxynivalenol and nivalenol. Results indicated trichothecene contamination in 90.08% of our samples, with deoxynivalenol predominating by at least 78% in each examined group. Co-occurrence of three or four trichothecenes were found in 23.85% of our samples. Our study underscores the necessity of consistent monitoring of staple foods to prevent the intake of harmful trichothecenes by consumers.

摘要

鉴于谷物中霉菌毒素的频繁出现,本研究评估了罗马尼亚市场上 121 个样本中是否存在单端孢霉烯族毒素。这些样品根据产品类型分为五类:(1)含白面粉的面包和烘焙产品,(2)含全麦面粉的半黑面包,(3)含黑麦面粉的黑面包,(4)意大利面,和(5)生小麦。气相色谱-质谱联用技术用于检测 13 种不同的霉菌毒素,包括 A 型化合物 HT-2 毒素和 T-2 毒素,以及 B 型化合物脱氧雪腐镰刀菌烯醇和雪腐镰刀菌烯醇。结果表明,我们的样品中有 90.08%受到单端孢霉烯族毒素污染,每个检查组中至少有 78%是脱氧雪腐镰刀菌烯醇占优势。我们的样品中有 23.85%同时存在三种或四种单端孢霉烯族毒素。本研究强调了对主食进行持续监测的必要性,以防止消费者摄入有害的单端孢霉烯族毒素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3859/10467109/0620860cd9ba/toxins-15-00466-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3859/10467109/b4f3551c28c3/toxins-15-00466-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3859/10467109/0cc9c428ab0b/toxins-15-00466-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3859/10467109/299297ceea9e/toxins-15-00466-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3859/10467109/0620860cd9ba/toxins-15-00466-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3859/10467109/b4f3551c28c3/toxins-15-00466-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3859/10467109/0cc9c428ab0b/toxins-15-00466-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3859/10467109/299297ceea9e/toxins-15-00466-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3859/10467109/0620860cd9ba/toxins-15-00466-g004.jpg

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Type B Trichothecenes in Cereal Grains and Their Products: Recent Advances on Occurrence, Toxicology, Analysis and Post-Harvest Decontamination Strategies.谷物及其制品中的 B 型单端孢霉烯族化合物:研究进展、毒理学、分析及收获后减毒策略。
Toxins (Basel). 2023 Jan 17;15(2):85. doi: 10.3390/toxins15020085.
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Contamination of Wheat, Barley, and Maize Seeds with Toxigenic Fusarium Species and Their Mycotoxins in Tunisia.突尼斯小麦、大麦和玉米种子的产毒镰刀菌物种污染及其真菌毒素。
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Sub-acute oral exposure to lowest observed adverse effect level of nivalenol exacerbates atopic dermatitis in mice via direct activation of mitogen-activated protein kinase signal in antigen-presenting cells.亚急性口服最低观察到的有害作用水平的雪腐镰刀菌烯醇可通过抗原呈递细胞中丝裂原活化蛋白激酶信号的直接激活加重小鼠特应性皮炎。
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