Sacchettino Luigi, Giuliano Viviana Orsola, Avallone Luigi, Napolitano Francesco, d'Angelo Danila
Department of Veterinary Medicine and Animal Production, University of Naples Federico II, 80137 Naples, Italy.
Independent Researcher, 81100 Caserta, Italy.
Vet Sci. 2023 Jul 4;10(7):435. doi: 10.3390/vetsci10070435.
Behavioral dysfunctions in dogs represent a critical issue of the human-animal relationship. In particular, aggression can make interspecific coexistence quite complicated within family units, thus exposing all members to greater health risks. In this present study, we documented multiple aggression episodes against one of the two family members caused by a 4-year-old neutered male pure breed Lagotto Romagnolo dog. To minimize impulsivity and anxiety-like behaviors of the patient as much as possible and improve his relationship with the adopting family, we used an interdisciplinary approach, employing specific skilled personnel, including a veterinary behaviorist and a rehabilitating dog instructor. Nine months after fluoxetine treatment (0.8 mg/kg, SID), in combination with oral α-s1 casozepine administration, and behavioral rehabilitation, the owners reported a significant reduction in aggressive events in terms of intensity and frequency. Collectively, our promising data pave the way toward a more detailed characterization of α-s1-casozepine to better evaluate the potential involvement of such a compound in the modulation of aggressive behaviors in dogs affected by relational dysfunctions.
犬类的行为功能障碍是人与动物关系中的一个关键问题。特别是，攻击性会使家庭单位内的种间共存变得相当复杂，从而使所有成员面临更大的健康风险。在本研究中，我们记录了一只4岁绝育的雄性纯种罗马诺水犬对两名家庭成员之一的多次攻击事件。为了尽可能减少患者的冲动性和焦虑样行为，并改善它与收养家庭的关系，我们采用了跨学科方法，聘请了包括兽医行为学家和犬类康复训练师在内的专业技术人员。在氟西汀（0.8 mg/kg，每日一次）治疗九个月后，结合口服α-s1酪蛋白，以及行为康复训练，主人报告说攻击事件在强度和频率上都显著减少。总体而言，我们的这些有前景的数据为更详细地描述α-s1酪蛋白铺平了道路，以便更好地评估这种化合物在调节受关系功能障碍影响的犬类攻击行为中的潜在作用。
