Maugeri Grazia, Amato Alessandra, Sortino Martina, D Agata Velia, Musumeci Giuseppe
Section of Anatomy, Histology and Movement Sciences, Department of Biomedical and Biotechnological Sciences, University of Catania, 95123 Catania, Italy.
Research Center on Motor Activities (CRAM), University of Catania, 95123 Catania, Italy.
Antioxidants (Basel). 2023 Jul 8;12(7):1401. doi: 10.3390/antiox12071401.
Spinal cord injury (SCI) is an irreversible disease resulting in partial or total loss of sensory and motor function. The pathophysiology of SCI is characterized by an initial primary injury phase followed by a secondary phase in which reactive oxygen species (ROSs) and associated oxidative stress play hallmark roles. Physical exercise is an indispensable means of promoting psychophysical well-being and improving quality of life. It positively influences the neuromuscular, cardiovascular, respiratory, and immune systems. Moreover, exercise may provide a mechanism to regulate the variation and equilibrium between pro-oxidants and antioxidants. After a brief overview of spinal cord anatomy and the different types of spinal cord injury, the purpose of this review is to investigate the evidence regarding the effect of exercise on oxidative stress among individuals with SCI.
脊髓损伤（SCI）是一种不可逆的疾病，会导致感觉和运动功能部分或完全丧失。SCI的病理生理学特征是最初的原发性损伤阶段，随后是继发性阶段，其中活性氧（ROS）和相关的氧化应激起主要作用。体育锻炼是促进身心健康和提高生活质量不可或缺的手段。它对神经肌肉、心血管、呼吸和免疫系统有积极影响。此外，运动可能提供一种机制来调节促氧化剂和抗氧化剂之间的变化和平衡。在简要概述脊髓解剖结构和不同类型的脊髓损伤后，本综述的目的是研究关于运动对SCI患者氧化应激影响的证据。
