Abdel-Kafy El-Sayed M, Kamel Kamel I, Severgnini Marco, Morsy Shama H A, Cremonesi Paola, Ghoneim Shereen S, Brecchia Gabriele, Ali Neama I, Abdel-Ghafar Yasmein Z, Ali Wael A H, Shabaan Hoda M A
Animal Production Research Institute (APRI), Agricultural Research Center (ARC), Dokki, Giza 12651, Egypt.
Institute of Biomedical Technologies, National Research Council (ITB-CNR), Via f.lli Cervi, 93, 20054 Segrate, Italy.
Animals (Basel). 2023 Jul 13;13(14):2294. doi: 10.3390/ani13142294.
This study aimed to evaluate the productive performance and microbiota variation in the jejunum and cecum of two rabbit breeds with different growth rates. This study was carried out on Native Middle-Egypt Breed (NMER) and Giant Flanders (GF) rabbits from 5 weeks to 12 weeks of age. Twenty NMER (NM) and GF male rabbits were slaughtered, and the jejunum and cecum tracts were collected to assay gut microbiota composition via 16S ribosomal RNA (rRNA) gene sequencing and histology examination. At 12 weeks of age, daily weight gain, villus height in the jejunum, total protein, and albumin were higher in GF rabbits than in NMER rabbits. Also, the jejunal villi of GF were well arranged in their dense borders. The microbiota between the jejunum and cecum was significantly different in terms of Beta-diversity. A significant correlation between (jejunum NM samples) and (cecum GF samples) with body weight and weight gain was found ( < 0.05). Moreover, Escherichia-Shigella in the cecum of NM was significantly correlated with weight gain ( < 0.05). The most abundant genera identified in the jejunal and cecal contents of GF were generally beneficial microbiota. They may also play a role in reducing the pathogenic effects of in these rabbits.
本研究旨在评估两种生长速率不同的兔品种空肠和盲肠的生产性能及微生物群变化。本研究以5周龄至12周龄的埃及本土中品种（NMER）和巨型佛兰德（GF）兔为对象。屠宰20只NMER（NM）和GF雄性兔，收集空肠和盲肠段，通过16S核糖体RNA（rRNA）基因测序和组织学检查分析肠道微生物群组成。12周龄时，GF兔的日增重、空肠绒毛高度、总蛋白和白蛋白均高于NMER兔。此外，GF兔空肠绒毛在其致密边缘排列良好。空肠和盲肠之间的微生物群在β多样性方面存在显著差异。发现（空肠NM样本）和（盲肠GF样本）与体重和体重增加之间存在显著相关性（<0.05）。此外，NM兔盲肠中的埃希氏菌-志贺氏菌与体重增加显著相关（<0.05）。在GF兔的空肠和盲肠内容物中鉴定出的最丰富的属通常是有益微生物群。它们也可能在减轻这些兔子中 的致病作用方面发挥作用。
