Octavius Gilbert Sterling, Daleni Vamela Adman, Sagala Yulita Delfia Sari
Department of Pediatrics, Universitas Pelita Harapan, Tangerang 15811, Indonesia.
St. Theresia Hospital, Jambi 36123, Indonesia.
Children (Basel). 2023 Jul 13;10(7):1216. doi: 10.3390/children10071216.
Due to high entry barriers, countries might find it daunting to implement the NBS program, especially those just trying to start it. This review aims to discuss Indonesia's barriers that hinder newborn screening (NBS) implementation while discussing the future implications. Literature in Pubmed and Google Scholar was scoured with keywords such as "Newborn Screening", "Neonatal Screening", "Indonesia", "Asia Pacific", "Barriers", and "Challenges". We also searched for relevant references in those published articles. Grey literature, such as state regulations, informative webinars on the topics by experts regarding current situations, and press releases by the Indonesian Minister of Health (MoH), was also searched. Newborn screening is no longer considered just a laboratory test but an array of well-harmonized systems that must be orchestrated well. Some of the barriers Indonesia faces in implementing NBS are a lack of prevalence data, ethical issues, infrastructure, cost-benefit analysis, logistical issues, government support, patient issues, a lack of commitments, and a lack of healthcare workers, specialization, and training. Government support with professional advocates and support groups, proper infrastructure, and a single-payer system for NBS programs are necessary to accelerate NBS programs in Indonesia.
由于进入壁垒较高，各国可能会发现实施新生儿筛查项目颇具挑战性，尤其是那些刚刚开始尝试的国家。本综述旨在探讨阻碍印度尼西亚新生儿筛查（NBS）实施的障碍，并讨论其未来影响。我们在PubMed和谷歌学术中搜索了“新生儿筛查”、“新生儿筛查”、“印度尼西亚”、“亚太地区”、“障碍”和“挑战”等关键词的文献。我们还在这些已发表文章中搜索了相关参考文献。我们还搜索了灰色文献，如国家法规、专家关于当前形势的主题信息网络研讨会以及印度尼西亚卫生部的新闻稿。新生儿筛查不再仅仅被视为一项实验室检测，而是一系列必须精心协调的完善系统。印度尼西亚在实施新生儿筛查时面临的一些障碍包括缺乏患病率数据、伦理问题、基础设施、成本效益分析、后勤问题、政府支持、患者问题、缺乏承诺以及缺乏医护人员、专业技能和培训。政府通过专业倡导者和支持团体提供支持、完善基础设施以及建立新生儿筛查项目的单一支付系统对于加速印度尼西亚的新生儿筛查项目是必要的。
