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Regulatory Clearance and Approval of Therapeutic Protocols of Transcranial Magnetic Stimulation for Psychiatric Disorders.

作者信息

Cotovio Gonçalo, Ventura Fabiana, Rodrigues da Silva Daniel, Pereira Patrícia, Oliveira-Maia Albino J

机构信息

Champalimaud Research and Clinical Centre, Champalimaud Foundation, 1400-038 Lisbon, Portugal.

NOVA Medical School, Faculdade de Ciências Médicas, NMS, FCM, Universidade NOVA de Lisboa, 1169-056 Lisbon, Portugal.

出版信息

Brain Sci. 2023 Jul 5;13(7):1029. doi: 10.3390/brainsci13071029.


DOI:10.3390/brainsci13071029
PMID:37508962
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10377201/
Abstract

Non-invasive brain stimulation techniques (NIBS) have been widely used in both clinical and research contexts in neuropsychiatry. They are safe and well-tolerated, making NIBS an interesting option for application in different settings. Transcranial magnetic stimulation (TMS) is one of these strategies. It uses electromagnetic pulses for focal modulate ion of neuronal activity in brain cortical regions. When pulses are applied repeatedly (repetitive transcranial magnetic stimulation-rTMS), they are thought to induce long-lasting neuroplastic effects, proposed to be a therapeutic mechanism for rTMS, with efficacy and safety initially demonstrated for treatment-resistant depression (TRD). Since then, many rTMS treatment protocols emerged for other difficult to treat psychiatric conditions. Moreover, multiple clinical studies, including large multi-center trials and several meta-analyses, have confirmed its clinical efficacy in different neuropsychiatric disorders, resulting in evidence-based guidelines and recommendations. Currently, rTMS is cleared by multiple regulatory agencies for the treatment of TRD, depression with comorbid anxiety disorders, obsessive compulsive disorder, and substance use disorders, such as smoking cessation. Importantly, current research supports the potential future use of rTMS for other psychiatric syndromes, including the negative symptoms of schizophrenia and post-traumatic stress disorder. More precise knowledge of formal indications for rTMS therapeutic use in psychiatry is critical to enhance clinical decision making in this area.

摘要

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[9]
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本文引用的文献

[1]
Preclinical modeling in depression and anxiety: Current challenges and future research directions.

Adv Clin Exp Med. 2023-5

[2]
Clinical diagnostic utility of transcranial magnetic stimulation in neurological disorders. Updated report of an IFCN committee.

Clin Neurophysiol. 2023-6

[3]
Fear-induced bradycardia in mental disorders: Foundations, current advances, future perspectives.

Neurosci Biobehav Rev. 2023-6

[4]
Neuropharmacological Modulation of N-methyl-D-aspartate, Noradrenaline and Endocannabinoid Receptors in Fear Extinction Learning: Synaptic Transmission and Plasticity.

Int J Mol Sci. 2023-3-21

[5]
Exploring Novel Therapeutic Targets in the Common Pathogenic Factors in Migraine and Neuropathic Pain.

Int J Mol Sci. 2023-2-18

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Symptom provocation for treatment of obsessive-compulsive disorder using transcranial magnetic stimulation: A step-by-step guide for professional training.

Front Psychiatry. 2022-8-3

[7]
In Older Adults the Antidepressant Effect of Repetitive Transcranial Magnetic Stimulation Is Similar but Occurs Later Than in Younger Adults.

Front Aging Neurosci. 2022-7-19

[8]
Psychiatric Applications of Repetitive Transcranial Magnetic Stimulation.

Focus (Am Psychiatr Publ). 2022-1

[9]
Assessment of Noninvasive Brain Stimulation Interventions for Negative Symptoms of Schizophrenia: A Systematic Review and Network Meta-analysis.

JAMA Psychiatry. 2022-8-1

[10]
Transcranial Magnetic Stimulation in the Treatment of Neurological Diseases.

Front Neurol. 2022-5-20

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