糖尿病肾病生物标志物在预测代谢相关脂肪性肝病中的意义
Significance of Diabetic Kidney Disease Biomarkers in Predicting Metabolic-Associated Fatty Liver Disease.
作者信息
Bae Jaehyun, Lee Byung-Wan
机构信息
Division of Endocrinology and Metabolism, Department of Internal Medicine, Catholic Kwandong University College of Medicine, International St. Mary's Hospital, Incheon 22711, Republic of Korea.
Division of Endocrinology and Metabolism, Department of Internal Medicine, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
出版信息
Biomedicines. 2023 Jul 7;11(7):1928. doi: 10.3390/biomedicines11071928.
Metabolic-associated fatty liver disease (MAFLD) and diabetic kidney disease (DKD) share various pathophysiological factors, and epidemiological evidence suggests that these two diseases are associated. Albuminuria and the estimated glomerular filtration rate, which are conventional biomarkers of DKD, are reportedly associated with the risk or severity of MAFLD. Recently, novel DKD biomarkers reflecting renal tubular injury have been introduced to complement conventional DKD markers. In this article, we looked at previous studies that showed an association between MAFLD and DKD, and also reviewed the significance of DKD biomarkers as predictive risk factors for MAFLD.
代谢相关脂肪性肝病（MAFLD）和糖尿病肾病（DKD）具有多种共同的病理生理因素，流行病学证据表明这两种疾病存在关联。据报道，作为DKD传统生物标志物的蛋白尿和估计肾小球滤过率与MAFLD的风险或严重程度相关。最近，反映肾小管损伤的新型DKD生物标志物已被引入，以补充传统的DKD标志物。在本文中，我们回顾了先前显示MAFLD与DKD之间存在关联的研究，并探讨了DKD生物标志物作为MAFLD预测风险因素的意义。
Zotero 插件