新冠长期症状的神经和精神表现及其[F]FDG PET检查结果：综述

Hameed Rizwanullah, Bahadur Anuradha Rosario, Singh Shashi Bhushan, Sher Juwairah, Todua Maia, Moradi Leah Mahsa, Bastakoti Sanjiv, Arslan Maeen, Ajmal Hanfa, Lee Gha Young, Ayubcha Cyrus, Werner Thomas J, Alavi Abass, Revheim Mona-Elisabeth

Kingsbrook Jewish Medical Center, 585 Schenectady Avenue, New York, NY 11203, USA.

Interfaith Medical Center, 1545 Atlantic Avenue, New York, NY 11213, USA.

Diagnostics (Basel). 2023 Jul 12;13(14):2353. doi: 10.3390/diagnostics13142353.

For more than two years, lingering sequalae of COVID-19 have been extensively investigated. Approximately 10% of individuals infected by COVID-19 have been found to experience long-term symptoms termed "long COVID-19". The neurological and psychiatric manifestations of long COVID-19 are of particular concern. While pathogenesis remains unclear, emerging imaging studies have begun to better elucidate certain pathological manifestation. Of specific interest is imaging with [F]FDG PET which directly reflects cellular glycolysis often linked to metabolic and inflammatory processes. Seeking to understand the molecular basis of neurological features of long COVID-19, this review encompasses the most recent [F]FDG PET literature in this area.

两年多来，新冠后遗症一直受到广泛研究。约10%的新冠感染者被发现出现了被称为“长新冠”的长期症状。长新冠的神经和精神表现尤其令人担忧。虽然发病机制尚不清楚，但新兴的影像学研究已开始更好地阐明某些病理表现。特别值得关注的是[F]FDG PET成像，它直接反映了通常与代谢和炎症过程相关的细胞糖酵解。为了了解长新冠神经特征的分子基础，本综述涵盖了该领域最新的[F]FDG PET文献。