雌激素受体在健康和疾病中的作用。
The Role of Estrogen Receptors in Health and Disease.
机构信息
Irset (Institut de Recherche en Santé, Environnement et Travail)-UMR_S 1085, EHESP, Inserm, Université de Rennes, F-35000 Rennes, France.
出版信息
Int J Mol Sci. 2023 Jul 12;24(14):11354. doi: 10.3390/ijms241411354.
Abstract
Many biological and physiological events, including growth, development, and metabolism of reproductive and non-reproductive tissues in men and women, are regulated by estrogens and estrogen receptors (ERs) [...].
摘要
许多生物和生理事件，包括男性和女性生殖和非生殖组织的生长、发育和代谢，都受到雌激素和雌激素受体（ERs）的调节[... ]。
相似文献
1
The Role of Estrogen Receptors in Health and Disease.雌激素受体在健康和疾病中的作用。
Int J Mol Sci. 2023 Jul 12;24(14):11354. doi: 10.3390/ijms241411354.
2
A comparative review on estrogen receptors in the reproductive male tract of non mammalian vertebrates.非哺乳类脊椎动物雄性生殖道中雌激素受体的比较综述
Steroids. 2018 Jun;134:1-8. doi: 10.1016/j.steroids.2018.04.001. Epub 2018 Apr 6.
3
Emerging Roles of Estrogen-Related Receptors in the Brain: Potential Interactions with Estrogen Signaling.雌激素相关受体在大脑中的新兴作用：与雌激素信号的潜在相互作用。
Int J Mol Sci. 2018 Apr 5;19(4):1091. doi: 10.3390/ijms19041091.
4
Expression and function of estrogen receptors and estrogen-related receptors in the brain and their association with Alzheimer's disease.脑内雌激素受体和雌激素相关受体的表达和功能及其与阿尔茨海默病的关系。
Front Endocrinol (Lausanne). 2023 Jul 4;14:1220150. doi: 10.3389/fendo.2023.1220150. eCollection 2023.
5
Missing Information from the Estrogen Receptor Puzzle: Where Are They Localized in Bull Reproductive Tissues and Spermatozoa?雌激素受体之谜中的缺失信息：它们在公牛生殖组织和精子中何处定位？
Cells. 2020 Jan 10;9(1):183. doi: 10.3390/cells9010183.
6
Estrogen in the male: a historical perspective.男性体内的雌激素：历史视角。
Biol Reprod. 2018 Jul 1;99(1):27-44. doi: 10.1093/biolre/ioy043.
7
To ERR in the estrogen pathway.在雌激素途径中出错。
Trends Endocrinol Metab. 2002 Jul;13(5):220-5. doi: 10.1016/s1043-2760(02)00592-1.
8
Interactions of estrogens and insulin-like growth factor-I in the brain: implications for neuroprotection.雌激素与胰岛素样生长因子-I在大脑中的相互作用：对神经保护的意义。
Brain Res Brain Res Rev. 2001 Nov;37(1-3):320-34. doi: 10.1016/s0165-0173(01)00137-0.
9
Impact of environmental estrogens on Yfish considering the diversity of estrogen signaling.考虑到雌激素信号的多样性，环境雌激素对鱼类的影响。
Gen Comp Endocrinol. 2013 Sep 15;191:190-201. doi: 10.1016/j.ygcen.2013.05.015. Epub 2013 Jun 11.
10
Suppression of estrogen actions in human lung cancer.抑制人肺癌中的雌激素作用。
Mol Cell Endocrinol. 2011 Jul 4;340(2):168-74. doi: 10.1016/j.mce.2011.02.018. Epub 2011 Feb 25.
引用本文的文献
1
Estrogen Receptor Enhancers Sensitive to Low Doses of Hormone Specify Distinct Molecular and Biological Outcomes.对低剂量激素敏感的雌激素受体增强子决定了不同的分子和生物学结果。
bioRxiv. 2025 Aug 12:2025.08.08.669412. doi: 10.1101/2025.08.08.669412.
2
Nuclear receptors in health and disease: signaling pathways, biological functions and pharmaceutical interventions.健康与疾病中的核受体：信号通路、生物学功能及药物干预
Signal Transduct Target Ther. 2025 Jul 28;10(1):228. doi: 10.1038/s41392-025-02270-3.
3
Developmental Endothelial Locus-1 Promotes Osteoclast Differentiation and Activation.发育性内皮位点-1促进破骨细胞分化和激活。
Int J Mol Sci. 2025 Mar 16;26(6):2673. doi: 10.3390/ijms26062673.
4
Neuroprotective Roles of Daidzein Through Extracellular Signal-Regulated Kinases Dependent Pathway In Chronic Unpredictable Mild Stress Mouse Model.大豆苷元通过细胞外信号调节激酶依赖性途径在慢性不可预测轻度应激小鼠模型中的神经保护作用
Mol Neurobiol. 2025 Apr;62(4):4899-4921. doi: 10.1007/s12035-024-04567-w. Epub 2024 Nov 4.
5
NLRC5 exerts anti-endometriosis effects through inhibiting ERβ-mediated inflammatory response.NLRC5 通过抑制 ERβ 介导的炎症反应发挥抗子宫内膜异位症作用。
BMC Med. 2024 Sep 2;22(1):351. doi: 10.1186/s12916-024-03571-0.
本文引用的文献
1
Early Inactivation of Membrane Estrogen Receptor Alpha (ERα) Recapitulates the Endothelial Dysfunction of Aged Mouse Resistance Arteries.早期失活膜雌激素受体α（ERα）可再现老年小鼠阻力动脉的内皮功能障碍。
Int J Mol Sci. 2022 Mar 5;23(5):2862. doi: 10.3390/ijms23052862.
2
Estradiol Signaling at the Heart of Folliculogenesis: Its Potential Deregulation in Human Ovarian Pathologies.雌激素信号在卵泡发生中的核心作用：其在人类卵巢病变中的潜在失调。
Int J Mol Sci. 2022 Jan 3;23(1):512. doi: 10.3390/ijms23010512.
3
Berberine Inhibits MDA-MB-231 Cells as an Agonist of G Protein-Coupled Estrogen Receptor 1.小檗碱作为 G 蛋白偶联雌激素受体 1 的激动剂抑制 MDA-MB-231 细胞。
Int J Mol Sci. 2021 Oct 24;22(21):11466. doi: 10.3390/ijms222111466.
4
HPTE-Induced Embryonic Thymocyte Death and Alteration of Differentiation Is Not Rescued by ERα or GPER Inhibition but Is Exacerbated by Concurrent TCR Signaling.HPTE 诱导的胚胎胸腺细胞死亡和分化改变不能被 ERα 或 GPER 抑制所挽救，但可被同时的 TCR 信号转导所加剧。
Int J Mol Sci. 2021 Sep 20;22(18):10138. doi: 10.3390/ijms221810138.
5
Voluntary Wheel Running Partially Compensates for the Effects of Global Estrogen Receptor-α Knockout on Cortical Bone in Young Male Mice.自愿转轮运动部分补偿了全球雌激素受体-α 敲除对年轻雄性小鼠皮质骨的影响。
Int J Mol Sci. 2021 Feb 9;22(4):1734. doi: 10.3390/ijms22041734.
6
ESR1 ChIP-Seq Identifies Distinct Ligand-Free ESR1 Genomic Binding Sites in Human Hepatocytes and Liver Tissue.ESR1 ChIP-Seq 鉴定出人肝细胞和肝组织中独特的无配体 ESR1 基因组结合位点。
Int J Mol Sci. 2021 Feb 2;22(3):1461. doi: 10.3390/ijms22031461.
7
Estrogen Receptor Signaling Pathways Involved in Invasion and Colony Formation of Androgen-Independent Prostate Cancer Cells PC-3.涉及雄激素非依赖性前列腺癌细胞 PC-3 侵袭和集落形成的雌激素受体信号通路。
Int J Mol Sci. 2021 Jan 25;22(3):1153. doi: 10.3390/ijms22031153.
8
A Closer Look at Estrogen Receptor Mutations in Breast Cancer and Their Implications for Estrogen and Antiestrogen Responses.深入探讨乳腺癌中的雌激素受体突变及其对雌激素和抗雌激素反应的影响。
Int J Mol Sci. 2021 Jan 13;22(2):756. doi: 10.3390/ijms22020756.
9
Estrogen Receptors: Therapeutic Perspectives for the Treatment of Cardiac Dysfunction after Myocardial Infarction.雌激素受体：心肌梗死后心脏功能障碍治疗的治疗学展望。
Int J Mol Sci. 2021 Jan 7;22(2):525. doi: 10.3390/ijms22020525.
10
The Role of Estrogen Receptors and Their Signaling across Psychiatric Disorders.雌激素受体及其信号传导在精神疾病中的作用
Int J Mol Sci. 2020 Dec 31;22(1):373. doi: 10.3390/ijms22010373.
Zotero 插件