山梨醇对大鼠胃肠道微生物区系的影响。

The effects of sorbitol on the gastrointestinal microflora in rats.

作者信息

Salminen S, Salminen E, Bridges J, Marks V

出版信息

Z Ernahrungswiss. 1986 Jun;25(2):91-5. doi: 10.1007/BF02020738.

DOI:10.1007/BF02020738

Abstract

The influence of dietary sorbitol on the quantity and quality of faecal microflora was studied in Wistar albino rats. The animals were gradually adapted to 20% dietary sorbitol or sucrose and faecal samples were analyzed for the numbers of major bacteria. No major changes in the numbers of total aerobic or anaerobic bacteria, aerobic streptococci and yeasts were observed after sorbitol feeding but sucrose appeared to decrease the total aerobes and anaerobes in the faeces. However, sorbitol feeding caused a clear shift in the rat faecal microbial population from gram-negative to gram-positive bacteria. All animals were capable of adapting to 20% dietary sorbitol or sucrose and withstood sorbitol treatment without problems.

摘要

在Wistar白化大鼠中研究了膳食山梨醇对粪便微生物群落数量和质量的影响。动物逐渐适应20%的膳食山梨醇或蔗糖，并对粪便样本中的主要细菌数量进行分析。喂食山梨醇后，需氧菌或厌氧菌、需氧链球菌和酵母菌的总数没有明显变化，但蔗糖似乎会减少粪便中的需氧菌和厌氧菌总数。然而，喂食山梨醇导致大鼠粪便微生物群落从革兰氏阴性菌明显转变为革兰氏阳性菌。所有动物都能够适应20%的膳食山梨醇或蔗糖，并且能顺利耐受山梨醇处理。