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低强度与高强度激光疗法作为膝关节骨关节炎辅助治疗的比较:一项随机双盲临床试验

Comparison between Low-Level and High-Intensity Laser Therapy as an Adjunctive Treatment for Knee Osteoarthritis: A Randomized, Double-Blind Clinical Trial.

作者信息

Ahmad Mohd Azzuan, Moganan Mageswari, A Hamid Mohamad Shariff, Sulaiman Norhuda, Moorthy Ushantini, Hasnan Nazirah, Yusof Ashril

机构信息

Physiotherapy Programme, Centre for Rehabilitation and Special Needs Studies, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Kuala Lumpur 50300, Malaysia.

Faculty of Sports and Exercise Science, Universiti Malaya, Kuala Lumpur 50603, Malaysia.

出版信息

Life (Basel). 2023 Jul 6;13(7):1519. doi: 10.3390/life13071519.

DOI:10.3390/life13071519
PMID:37511894
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10381799/
Abstract

BACKGROUND

Low-level (LLLT) and high-intensity laser therapy (HILT) can be beneficial additions to knee osteoarthritis (KOA) rehabilitation exercises; however, it is still being determined which electrophysical agent is more effective.

AIM

To compare the effects of LLLT and HILT as adjuncts to rehabilitation exercises (LL + EX and HL + EX) on clinical outcomes in KOA.

METHODS

Thirty-four adults with mild-to-moderate KOA were randomly allocated to either LL + EX or HL + EX ( = 17 each). Both groups underwent their respective intervention weekly for twelve weeks: LL + EX (400 mW, 830 nm, 10 to 12 J/cm, and 400 J per session) or HL + EX (5 W, 1064 nm, 19 to 150 J/cm, and 3190 J per session). The laser probe was placed vertically in contact with the knee and moved in a slow-scan manner on the antero-medial/lateral sides of the knee joint. Participants' Knee Injury and Osteoarthritis Outcome Score (KOOS), Numerical Pain Rating Scale (NPRS), active knee flexion, and Timed Up-and-Go test (TUG) were assessed.

RESULTS

Post intervention, both groups showed improvements in their KOOS, NPRS, active knee flexion, and TUG scores compared to baseline ( < 0.01). The mean difference of change in KOOS, NPRS, and active knee flexion scores for the HL + EX group surpassed the minimal clinically important difference threshold. In contrast, the LL + EX group only demonstrated clinical significance for the NPRS scores.

CONCLUSIONS

Incorporating HILT as an adjunct to usual KOA rehabilitation led to significantly higher improvements in pain, physical function, and knee-related disability compared to LLLT applied in scanning mode.

摘要

背景

低强度激光疗法(LLLT)和高强度激光疗法(HILT)可作为膝关节骨关节炎(KOA)康复锻炼的有益补充;然而,哪种电物理因子更有效仍有待确定。

目的

比较低强度激光疗法和高强度激光疗法作为康复锻炼辅助手段(LL + EX和HL + EX)对KOA临床结局的影响。

方法

34名轻度至中度KOA成人被随机分为LL + EX组或HL + EX组(每组17人)。两组均每周接受各自的干预,为期12周:LL + EX组(400 mW,830 nm,10至12 J/cm,每次400 J)或HL + EX组(5 W,1064 nm,19至150 J/cm,每次3190 J)。激光探头垂直放置与膝盖接触,并以慢扫描方式在膝关节的前内侧/外侧移动。评估参与者的膝关节损伤和骨关节炎结局评分(KOOS)、数字疼痛评分量表(NPRS)、主动膝关节屈曲度和计时起立行走测试(TUG)。

结果

干预后,与基线相比,两组的KOOS、NPRS、主动膝关节屈曲度和TUG评分均有所改善(P < 0.01)。HL + EX组KOOS、NPRS和主动膝关节屈曲度评分的变化平均差异超过最小临床重要差异阈值。相比之下,LL + EX组仅在NPRS评分上显示出临床意义。

结论

与以扫描模式应用的低强度激光疗法相比,将高强度激光疗法作为常规KOA康复的辅助手段,在疼痛、身体功能和膝关节相关残疾方面带来的改善显著更高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab60/10381799/43366eb93ec0/life-13-01519-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab60/10381799/1885c09cc41c/life-13-01519-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab60/10381799/b4ec04395b3d/life-13-01519-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab60/10381799/eeb6f77ff596/life-13-01519-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab60/10381799/28a0cd232828/life-13-01519-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab60/10381799/43366eb93ec0/life-13-01519-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab60/10381799/1885c09cc41c/life-13-01519-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab60/10381799/b4ec04395b3d/life-13-01519-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab60/10381799/eeb6f77ff596/life-13-01519-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab60/10381799/28a0cd232828/life-13-01519-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab60/10381799/43366eb93ec0/life-13-01519-g005.jpg

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