帕金森病患者营养状况与生活质量的相关性。
Correlations between Nutritional Status and Quality of Life of People with Parkinson's Disease.
机构信息
Neuroscience and Behaviour, Universidade Federal do Pará, Belém 66610-770, PA, Brazil.
Nutrition College, Universidade Federal do Pará, Belém 66610-770, PA, Brazil.
出版信息
Nutrients. 2023 Jul 24;15(14):3272. doi: 10.3390/nu15143272.
UNLABELLED
Parkinson's disease (PD) is a neurodegenerative condition that can impact the nutritional status, and such impact seems to be related to the quality of life (QoL).
OBJECTIVE
To evaluate the correlation between anthropometric variables and the QoL of people with Parkinson's disease (PD).
METHODS
This is a cross-sectional, descriptive, and analytical study, carried out through the collection of anthropometric data and application of the Parkinson's Disease Questionnaire PDQ-39.
RESULTS
33 individuals (23 male) diagnosed with PD participated in the research, with a mean age of 58.9 ± 11.6 years. We observed overweight in 45.4% of participants. The perception of QoL showed lower scores for the subjects in the dimensions of body discomfort (75.3 ± 16.6), social support (62.7 ± 15.7), and mobility (61.0 ± 23.6). The correlation between the total QoL score and age (model 1, B = 0.347; CI 0.004-0.902; = 0.048), which remained statistically significant in the multiple linear regression, regardless of gender (model 2, B = 0.365; CI 0.016-0.937; = 0.043) and BMI (model 3, B = 0.363; CI 0.006-0.943; = 0.047), suggests that, in the participants of this study, this relationship does not depend on gender and nutritional status.
CONCLUSION
The perception of QoL was worse in the dimensions of body discomfort, social support, and mobility, worsening with advanced age. Correlations between the worst scores in QoL dimensions and nutritional status were observed. A positive correlation was also identified between age and overall PDQ-39 score, regardless of gender and nutritional status.
目的
评估人体测量学变量与帕金森病（PD）患者生活质量（QoL）之间的相关性。
方法
这是一项横断面、描述性和分析性研究，通过收集人体测量学数据和应用帕金森病问卷 PDQ-39 进行。
结果
33 名（23 名男性）被诊断为 PD 的参与者参加了这项研究，平均年龄为 58.9 ± 11.6 岁。我们观察到 45.4%的参与者超重。在身体不适（75.3 ± 16.6）、社会支持（62.7 ± 15.7）和移动性（61.0 ± 23.6）等维度，QoL 的感知得分较低。QoL 总分与年龄之间存在相关性（模型 1，B = 0.347；CI 0.004-0.902； = 0.048），即使在考虑了性别（模型 2，B = 0.365；CI 0.016-0.937； = 0.043）和 BMI（模型 3，B = 0.363；CI 0.006-0.943； = 0.047）后，这种相关性在多线性回归中仍然具有统计学意义，这表明在本研究的参与者中，这种关系不受性别和营养状况的影响。
结论
在身体不适、社会支持和移动性等维度上，QoL 的感知更差，且随着年龄的增长而恶化。观察到 QoL 维度中最差评分与营养状况之间的相关性。还发现年龄与总体 PDQ-39 评分之间存在正相关，无论性别和营养状况如何。
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