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基于不同营养筛查或评估工具识别的营养不良对脑卒中患者功能结局的预测价值:系统评价和荟萃分析。

Predictive Value of Malnutrition, Identified via Different Nutritional Screening or Assessment Tools, for Functional Outcomes in Patients with Stroke: A Systematic Review and Meta-Analysis.

机构信息

School of Nursing, Jilin University, Changchun 130021, China.

The First Hospital of Jilin University, Changchun 130021, China.

出版信息

Nutrients. 2023 Jul 24;15(14):3280. doi: 10.3390/nu15143280.

DOI:10.3390/nu15143280
PMID:37513698
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10383200/
Abstract

BACKGROUND

Malnutrition affects more than half of patients with stroke. Although malnutrition leads to more deaths, a longer hospital stay, and higher costs, there is still a lack of consensus regarding the impact of malnutrition on physical functional outcomes in patients with stroke, and there are large differences in the diagnostic effects of nutritional screening or assessment tools for malnutrition. This study aimed to explore the impact of malnutrition in patients with stroke and assess the significance of current nutritional screening and assessment tools for these patients.

METHODS

Six databases were systematically searched until October 2022. Cohort studies meeting the eligibility criteria were included. Pooled effects were calculated using random-effects models.

RESULTS

Twenty-six studies with 21,115 participants were included. The pooled effects of malnutrition on poor functional outcome, FIM points, and dysphagia were OR = 2.72 (95% CI = 1.84-4.06), WMD = -19.42(95% CI = -32.87--5.96), and OR = 2.80 (95% CI = 1.67-4.67), respectively.

CONCLUSION

Malnutrition adversely affects the recovery of physical and swallowing functions in patients with stroke. Nutritional assessments consistently predict the outcomes of physical function in patients with stroke.

摘要

背景

营养不良影响超过一半的脑卒中患者。尽管营养不良会导致更多的死亡、更长的住院时间和更高的成本,但对于营养不良对脑卒中患者身体功能结局的影响仍缺乏共识,并且营养筛查或评估工具对营养不良的诊断效果存在很大差异。本研究旨在探讨脑卒中患者营养不良的影响,并评估当前营养筛查和评估工具对这些患者的意义。

方法

系统检索了六个数据库,直到 2022 年 10 月。纳入符合纳入标准的队列研究。使用随机效应模型计算合并效应。

结果

共纳入 26 项研究,共计 21115 名参与者。营养不良对不良功能结局、FIM 评分和吞咽困难的合并效应分别为 OR = 2.72(95%CI = 1.84-4.06),WMD = -19.42(95%CI = -32.87--5.96)和 OR = 2.80(95%CI = 1.67-4.67)。

结论

营养不良会对脑卒中患者身体和吞咽功能的恢复产生不利影响。营养评估一致预测脑卒中患者身体功能结局。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d187/10383200/a20298378643/nutrients-15-03280-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d187/10383200/2c574f2ab1c2/nutrients-15-03280-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d187/10383200/6a1c43c20224/nutrients-15-03280-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d187/10383200/a296d9f92fd3/nutrients-15-03280-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d187/10383200/a20298378643/nutrients-15-03280-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d187/10383200/2c574f2ab1c2/nutrients-15-03280-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d187/10383200/6a1c43c20224/nutrients-15-03280-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d187/10383200/a296d9f92fd3/nutrients-15-03280-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d187/10383200/a20298378643/nutrients-15-03280-g004.jpg

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Nutrients. 2023 Jan 29;15(3):683. doi: 10.3390/nu15030683.
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Evident lower blood levels of multiple nutritional compounds and highly prevalent malnutrition in sub-acute stroke patients with or without dysphagia.在伴有或不伴有吞咽困难的亚急性中风患者中,多种营养化合物的血液水平明显较低,且营养不良非常普遍。
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Combination of High Energy Intake and Intensive Rehabilitation Is Associated with the Most Favorable Functional Recovery in Acute Stroke Patients with Sarcopenia.
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