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猪繁殖与呼吸综合征病毒感染及适应性免疫应答机制的研究进展。

Progress in PRRSV Infection and Adaptive Immune Response Mechanisms.

机构信息

Wenzhou Key Laboratory for Virology and Immunology, Institute of Virology, Wenzhou University, Wenzhou 325035, China.

College of Food and Drugs, Luoyang Polytechnic, Luoyang 471099, China.

出版信息

Viruses. 2023 Jun 27;15(7):1442. doi: 10.3390/v15071442.

Abstract

Since its discovery, Porcine reproductive and respiratory syndrome (PRRS) has had a huge impact on the farming industry. The virus that causes PRRS is Porcine Reproductive and Respiratory Syndrome Virus (PRRSV), and because of its genetic diversity and the complexity of the immune response, the eradication of PRRS has been a challenge. To provide scientific references for PRRSV control and vaccine development, this study describes the processes of PRRSV-induced infection and escape, as well as the host adaptive immune response to PRRSV. It also discusses the relationship between PRRSV and the adaptive immune response.

摘要

自发现以来,猪繁殖与呼吸综合征(PRRS)对农业产业产生了巨大影响。引起 PRRS 的病毒是猪繁殖与呼吸综合征病毒(PRRSV),由于其遗传多样性和免疫反应的复杂性,根除 PRRS 一直是一个挑战。为了为 PRRSV 控制和疫苗开发提供科学参考,本研究描述了 PRRSV 诱导的感染和逃逸过程,以及宿主对 PRRSV 的适应性免疫反应。它还讨论了 PRRSV 与适应性免疫反应之间的关系。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e1c9/10385784/7293af39affa/viruses-15-01442-g001.jpg

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