Cezar Guilherme, Leite Fernando L, Fano Eduardo, Phillips Reid, Waddell John, Dion Kate, Magalhães Edison, Trevisan Giovani, Silva Gustavo, Linhares Daniel C
Department of Veterinary Diagnostic and Production Animal Medicine, Iowa State University, Ames, IA, United States.
Boehringer Ingelheim Animal Health USA Inc., Duluth, GA, United States.
Front Vet Sci. 2025 Jan 15;11:1535803. doi: 10.3389/fvets.2024.1535803. eCollection 2024.
Effective disease management strategies are essential for achieving optimal pig performance, ensuring high-quality animal health and welfare, and maintaining the economic viability of swine systems. Thus, understanding factors that lead to more or less severe disease are critically important. Porcine circovirus type 2 (PCV2) and () are endemic pathogens in the U.S., affecting herds with varying degrees of subclinical and clinical disease and impact on performance. While these are common pathogens, their interaction with PRRSV and performance has seldom been investigated. This study investigated the detection dynamics of , PRRSV, and PCV2, and their association with productivity impacts in wean-to-finish groups within a Midwest U.S. production system.
This observational field study involved batches of growing pigs from PRRSV-stable or PRRSV-negative sow farms. Oral fluids were collected longitudinally from weaning until market age, and tested using quantitative PCR for each of the aforementioned pathogens. The study included 36 batches with a total of 46,446 growing pigs, resulting in 4,000 oral fluid samples. Then, batches were categorized based on key performance indicators (mortality and average daily gain), PRRSV detection timing and total genomic copies of each pathogen.
Nineteen groups were characterized as high-performance and seventeen as low-performance. Mortality ranged from 5 to 9% in high-performance groups and 10.3-20.9% in low-performance groups. Average daily gain ranged from 0.68-0.86 kg in high-performance groups and 0.63-0.81 kg in low-performance groups. and PCV2 were detected in most groups, with significant differences in detection rates between high and low-performance groups. Groups with relatively high genomic copies of PCV2 and that had PRRSV detection presented higher mortality rates (15.75%).
This study expanded our understanding of PRRSV, PCV2, and co-detections and their impact on swine populations.
有效的疾病管理策略对于实现最佳的猪生长性能、确保高质量的动物健康和福利以及维持养猪系统的经济可行性至关重要。因此，了解导致疾病轻重程度不同的因素至关重要。2型猪圆环病毒（PCV2）和（此处原文缺失信息）是美国的地方性病原体，影响着不同程度的亚临床和临床疾病的猪群，并对生产性能产生影响。虽然这些是常见病原体，但它们与猪繁殖与呼吸综合征病毒（PRRSV）的相互作用以及对生产性能的影响很少被研究。本研究调查了（此处原文缺失信息）、PRRSV和PCV2的检测动态，以及它们与美国中西部生产系统中断奶至育肥猪群生产性能影响的关联。
这项观察性现场研究涉及来自PRRSV稳定或PRRSV阴性母猪场的生长猪批次。从断奶到上市年龄纵向收集口腔液，并使用定量PCR对上述每种病原体进行检测。该研究包括36个批次，共46446头生长猪，产生了4000份口腔液样本。然后，根据关键性能指标（死亡率和平均日增重）、PRRSV检测时间和每种病原体的总基因组拷贝数对批次进行分类。
19个组被归类为高性能组，17个组为低性能组。高性能组的死亡率在5%至9%之间，低性能组的死亡率在10.3%至20.9%之间。高性能组的平均日增重范围为0.68 - 0.86千克，低性能组为0.63 - 0.81千克。大多数组中检测到了（此处原文缺失信息）和PCV2，高性能组和低性能组的检测率存在显著差异。PCV2和（此处原文缺失信息）基因组拷贝数相对较高且检测到PRRSV的组死亡率较高（15.75%）。
本研究扩展了我们对PRRSV、PCV2和（此处原文缺失信息）共同检测及其对猪群影响的理解。
