BIO-IT Foundry Technology Institute, Pusan National University, Busan 46241, Republic of Korea.
SUNJE HI TEK Co., Ltd., Busan 46047, Republic of Korea.
Viruses. 2023 Jun 28;15(7):1463. doi: 10.3390/v15071463.
Germicidal lamps that primarily emit 254 nm ultraviolet (UV) radiation have been effectively utilized for surface sterilization, but they cannot be used on human skin and eyes due to their harmful and genotoxic activity. Recent reports have shown that far UV-C light (207-222 nm) can efficiently kill pathogens with potentially no harm to exposed human tissues. However, these methods still require additional filtering and/or further protective equipment. In this study, we demonstrate a filter-free, harmless, and single-wavelength far UV-C 207 nm germicidal light source that can be used to inactivate different respiratory viruses. It can be exploited as a safe and effective disinfection tool for various airborne viruses. We successfully developed a single-wavelength far UV-C source that produces an exact wavelength of 207 nm. We examined its safety on human skin and corneal cell lines, as well as its effects on inactivating different airborne viruses, such as coronavirus, adenovirus, and vaccinia virus. We expect that our far UV-C lamps can be safely and conveniently used to reduce COVID-19 infections and protect both our living spaces and hospitals from the threat of contamination by possible new or mutant viruses.
主要发射 254nm 紫外线（UV）辐射的杀菌灯已被有效地用于表面消毒，但由于其有害和遗传毒性活性，不能用于人体皮肤和眼睛。最近的报告表明，远 UV-C 光（207-222nm）可以有效地杀死病原体，而对暴露的人体组织几乎没有伤害。然而，这些方法仍然需要额外的过滤和/或进一步的防护设备。在本研究中，我们展示了一种无滤光片、无害、单波长的远 UV-C207nm 杀菌光源，可用于灭活不同的呼吸道病毒。它可以被开发为一种安全有效的消毒工具，用于各种空气传播病毒。我们成功开发了一种单波长远 UV-C 光源，产生精确的 207nm 波长。我们研究了它对人体皮肤和角膜细胞系的安全性，以及它对不同空气传播病毒（如冠状病毒、腺病毒和牛痘病毒）的灭活效果。我们期望我们的远 UV-C 灯可以安全方便地用于减少 COVID-19 的感染，并保护我们的生活空间和医院免受可能的新病毒或突变病毒的污染威胁。
