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超声引导竖脊肌平面阻滞对肥胖患者腹腔镜袖状胃切除术术后恢复的影响:一项随机对照试验。

Effect of Ultrasound-guided Erector Spinae Plane Block on Recovery After Laparoscopic Sleeve Gastrectomy in Patients With Obesity: A Randomized Controlled Trial.

机构信息

Department of Anesthesiology and Perioperative Medicine, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou, Henan Province, China.

Department of Anesthesiology, International Peace Maternity and Child Health Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Municipal Key Clinical Specialty, Shanghai, China.

出版信息

Clin Ther. 2023 Sep;45(9):894-900. doi: 10.1016/j.clinthera.2023.07.010. Epub 2023 Jul 27.

Abstract

PURPOSE

Previous research has not evaluated the potential effect of erector spinae plane block (ESPB) on quality of recovery (QoR) after laparoscopic sleeve gastrectomy. Therefore, we investigated the effect of an ultrasound-guided ESPB performed on patients with obesity who have undergone laparoscopic sleeve gastrectomy, measured using the 15-item QoR (QoR-15) scale.

METHODS

A total of 172 patients were enrolled in the study who were aged 18 to 65 years, had a body mass index ≥30 kg/m², were classified as having American Society of Anaesthesiologists physical status Ⅱ to Ⅲ, and had undergone laparoscopic sleeve gastrectomy. The patients were randomly divided into an ESPB group and a sham group (treated with normal saline). The primary outcome was the QoR-15 score, measured using the questionnaire 24 and 48 hours after surgery. The secondary outcomes were postoperative pain score, postoperative cumulative analgesic drug consumption, number of patient-controlled analgesia (PCA) requests, rate of rescue analgesia required at 48 hours, incidence of respiratory complications, and nerve block-related complications. The time of discharge from the postanesthesia care unit, postoperative activity, and length of stay at the hospital were also recorded.

FINDINGS

There was no significant difference in the global QoR-15 scores 24 and 48 hours after the operation. However, the groups' subdimension scores for the emotional state in QoR-15 at 24 and 48 hours after surgery were statistically different (P < 0.05). Meanwhile, patients in the ESPB group who indicated they were "feeling rested" at 24 and 48 hours after surgery and "having a feeling of general well-being" at 24 hours after surgery were significantly better than those in the sham group (P < 0.05). Compared with the sham group, participants in the ESPB group had lower resting pain scores at 6 and 12 hours after surgery and lower movement pain scores at 6, 12, 24, and 36 hours after surgery (P < 0.05). There was no statistical difference between the groups in postoperative cumulative analgesic drug consumption, number of PCA requests, incidence of respiratory complications, time of discharge from the postanesthesia care unit, or postoperative activity.

IMPLICATIONS

Our results indicate that a single ESPB does not improve the global QoR-15 scores after laparoscopic sleeve gastrectomy. However, the visual analog scale score for postoperative pain is reduced.

摘要

目的

先前的研究并未评估竖脊肌平面阻滞(ESPB)对腹腔镜袖状胃切除术患者术后恢复质量(QoR)的潜在影响。因此,我们通过使用 15 项 QoR(QoR-15)量表,研究了肥胖患者接受腹腔镜袖状胃切除术后接受超声引导的 ESPB 的效果。

方法

本研究共纳入 172 名年龄在 18 至 65 岁之间、BMI≥30kg/m²、美国麻醉医师协会身体状况分级为Ⅱ至Ⅲ级、接受腹腔镜袖状胃切除术的患者。患者被随机分为 ESPB 组和 sham 组(给予生理盐水)。主要结局为术后 24 和 48 小时使用问卷测量的 QoR-15 评分。次要结局为术后疼痛评分、术后累积镇痛药物消耗量、患者自控镇痛(PCA)请求次数、48 小时时需要解救镇痛的比例、呼吸并发症发生率以及神经阻滞相关并发症。还记录了麻醉后护理病房出院时间、术后活动以及住院时间。

结果

术后 24 和 48 小时时,两组的全球 QoR-15 评分无显著差异。然而,两组在术后 24 和 48 小时时 QoR-15 的情绪状态子维度评分存在统计学差异(P<0.05)。同时,ESPB 组在术后 24 和 48 小时时表示“感觉休息良好”以及在术后 24 小时时表示“感觉整体良好”的患者明显优于 sham 组(P<0.05)。与 sham 组相比,ESPB 组在术后 6 和 12 小时时静息疼痛评分较低,在术后 6、12、24 和 36 小时时运动疼痛评分较低(P<0.05)。两组在术后累积镇痛药物消耗量、PCA 请求次数、呼吸并发症发生率、麻醉后护理病房出院时间或术后活动方面无统计学差异。

结论

我们的研究结果表明,单次 ESPB 不能提高腹腔镜袖状胃切除术后的整体 QoR-15 评分。但是,术后疼痛的视觉模拟评分降低。

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