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大血管血管炎的高级分子影像学:将 FDG-PET 纳入临床工作流程。

Advanced molecular imaging in large-vessel vasculitis: Adopting FDG-PET into a clinical workflow.

机构信息

Nuclear Medicine Department, Medical College of Georgia, Augusta, GA, USA.

National Institutes of Arthritis and Musculoskeletal and Skin Diseases, Bethesda, MD, USA.

出版信息

Best Pract Res Clin Rheumatol. 2023 Mar;37(1):101856. doi: 10.1016/j.berh.2023.101856. Epub 2023 Jul 27.

Abstract

The use of fluorodeoxyglucose-positron emission tomography (FDG-PET) imaging to detect vascular inflammation is increasingly common in the clinical management of patients with large-vessel vasculitis (LVV). In this review, the role of FDG-PET imaging to diagnose and monitor vascular disease activity will be detailed. Suggestions on incorporation of FDG-PET imaging into a clinical workflow will be provided with emphasis on patient preparation, image acquisition, and image interpretation. If FDG-PET imaging is obtained, multimodal imaging assessment, whereby FDG-PET imaging and non-invasive angiography are obtained concurrently, and correlation of imaging findings with clinical assessment is generally advisable. Considering the clinical scenario and treatment status of the patient is important when interpreting vascular FDG-PET image findings.

摘要

氟代脱氧葡萄糖正电子发射断层扫描(FDG-PET)成像在大血管血管炎(LVV)患者的临床管理中越来越多地用于检测血管炎症。在本综述中,将详细介绍 FDG-PET 成像在诊断和监测血管疾病活动中的作用。将提供有关将 FDG-PET 成像纳入临床工作流程的建议,重点是患者准备、图像采集和图像解释。如果获得 FDG-PET 成像,则建议进行多模态成像评估,即同时获得 FDG-PET 成像和非侵入性血管造影,并通常将成像发现与临床评估相关联。在解释血管 FDG-PET 图像发现时,考虑患者的临床情况和治疗状态非常重要。

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