来自 5 周心率变异性生物反馈随机临床试验的多模态神经影像学数据。
Multimodal neuroimaging data from a 5-week heart rate variability biofeedback randomized clinical trial.
机构信息
University of Southern California, Los Angeles, CA, 90007, USA.
University of California, Irvine, USA.
出版信息
Sci Data. 2023 Jul 29;10(1):503. doi: 10.1038/s41597-023-02396-5.
We present data from the Heart Rate Variability and Emotion Regulation (HRV-ER) randomized clinical trial testing effects of HRV biofeedback. Younger (N = 121) and older (N = 72) participants completed baseline magnetic resonance imaging (MRI) including T-weighted, resting and emotion regulation task functional MRI (fMRI), pulsed continuous arterial spin labeling (PCASL), and proton magnetic resonance spectroscopy (H MRS). During fMRI scans, physiological measures (blood pressure, pulse, respiration, and end-tidal CO) were continuously acquired. Participants were randomized to either increase heart rate oscillations or decrease heart rate oscillations during daily sessions. After 5 weeks of HRV biofeedback, they repeated the baseline measurements in addition to new measures (ultimatum game fMRI, training mimicking during blood oxygen level dependent (BOLD) and PCASL fMRI). Participants also wore a wristband sensor to estimate sleep time. Psychological assessment comprised three cognitive tests and ten questionnaires related to emotional well-being. A subset (N = 104) provided plasma samples pre- and post-intervention that were assayed for amyloid and tau. Data is publicly available via the OpenNeuro data sharing platform.
我们呈现了心率变异性和情绪调节（HRV-ER）随机临床试验的数据，该试验测试了心率变异性生物反馈的效果。年轻（N=121）和年长（N=72）参与者完成了基线磁共振成像（MRI），包括 T 加权、静息和情绪调节任务功能磁共振成像（fMRI）、脉冲连续动脉自旋标记（PCASL）和质子磁共振波谱（H MRS）。在 fMRI 扫描期间，连续采集生理测量值（血压、脉搏、呼吸和呼气末 CO）。参与者被随机分配到在日常治疗中增加心率波动或减少心率波动。经过 5 周的心率变异性生物反馈治疗后，他们除了重复基线测量外，还进行了新的测量（最后通牒游戏 fMRI、训练模拟血氧水平依赖（BOLD）和 PCASL fMRI）。参与者还佩戴腕带传感器来估计睡眠时间。心理评估包括三个认知测试和十个与情绪健康相关的问卷。一部分（N=104）提供了干预前后的血浆样本，这些样本用于检测淀粉样蛋白和 tau。数据通过 OpenNeuro 数据共享平台公开提供。
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