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建立新加坡学龄儿童的颈性前庭诱发肌源性电位(cVEMP)正常数据。

Establishing cervical vestibular evoked myogenic potential (cVEMP) normative data in Singapore school-aged children.

机构信息

Audiology Program, Yong Loo Lin School of Medicine, National University of Singapore, Block MD 7, #03-12, 8 Medical Drive, 117596, Singapore.

Otolaryngology - Head & Neck Surgery Department, National University Hospital, 119074, Singapore.

出版信息

Int J Pediatr Otorhinolaryngol. 2023 Sep;172:111686. doi: 10.1016/j.ijporl.2023.111686. Epub 2023 Jul 25.

Abstract

OBJECTIVES

The Cervical Vestibular Evoked Myogenic Potential (cVEMP) is often employed in routine clinical practice as part of the vestibular test battery assessments. However, there is currently no well-established paediatric cVEMP normative data in Singapore. Additionally, limited literature has examined the relationship between neck length and cVEMP parameters. The main aims of this study are to 1) establish cVEMP normative data from Singaporean school-aged children aged 6-12 years old, and 2) examine if there is a significant correlation between neck length and cVEMP parameters.

METHODS

31 healthy children participated in this study. Every participant was screened to ensure that they had normal auditory and vestibular profiles before completing the cVEMP procedure, which involved 500 Hz tone burst through insertphones and head elevation from supine position as the method of neck contraction.

RESULTS

The response rate in 62 ears was 98.4% at 95 dBnHL and 100% at 100 dBnHL. The mean P1 and N1 latencies were 13.96 ± 1.17 m s and 21.50 ± 1.66 m s, with a mean corrected P1-N1 amplitude of 0.88 ± 0.34, and mean asymmetry ratio of 13 ± 10%. Median threshold was 80 dBnHL. Significant positive correlation between neck length and both P1, N1 latencies, and significant negative correlation between neck length and corrected P1-N1 amplitude were observed.

CONCLUSIONS

cVEMP paediatric normative data has been established for Singaporean school-aged children. The study also confirmed that neck length did have a significant influence on both latencies and corrected amplitude.

摘要

目的

颈源性前庭诱发肌源性电位(cVEMP)常作为前庭测试组合评估的一部分,用于常规临床实践。然而,目前新加坡还没有建立完善的儿科 cVEMP 正常参考值数据。此外,有限的文献研究了颈部长度与 cVEMP 参数之间的关系。本研究的主要目的是:1)建立新加坡学龄儿童(6-12 岁)的 cVEMP 正常参考值数据,2)检查颈部长度与 cVEMP 参数之间是否存在显著相关性。

方法

31 名健康儿童参与了本研究。所有参与者在完成 cVEMP 程序之前都进行了筛查,以确保他们具有正常的听觉和前庭功能。cVEMP 程序涉及使用插入式耳机通过 500Hz 短音爆裂和从仰卧位抬头的方式进行颈部收缩。

结果

在 95dBnHL 时,62 只耳朵的反应率为 98.4%,在 100dBnHL 时为 100%。平均 P1 和 N1 潜伏期分别为 13.96±1.17ms 和 21.50±1.66ms,平均校正 P1-N1 振幅为 0.88±0.34,平均不对称比为 13±10%。中位阈值为 80dBnHL。观察到颈部长度与 P1、N1 潜伏期呈显著正相关,与校正 P1-N1 振幅呈显著负相关。

结论

已为新加坡学龄儿童建立了 cVEMP 儿科正常参考值数据。该研究还证实,颈部长度确实对潜伏期和校正幅度都有显著影响。

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