Quantitative Diagnostic Imaging, Field of Oral and Maxillofacial Imaging and Histopathological Diagnostics, Course of Applied Science, The Nippon Dental University Graduate School of Life Dentistry at Niigata, Niigata, Japan.
Quantitative Diagnostic Imaging, Field of Oral and Maxillofacial Imaging and Histopathological Diagnostics, Course of Applied Science, The Nippon Dental University Graduate School of Life Dentistry at Niigata, Niigata, Japan; Department of Oral and Maxillofacial Radiology, The Nippon Dental University School of Life Dentistry at Niigata, Niigata, Japan.
Oral Surg Oral Med Oral Pathol Oral Radiol. 2023 Dec;136(6):753-758. doi: 10.1016/j.oooo.2023.06.012. Epub 2023 Jun 28.
We investigated the efficacy of using diffusion-weighted imaging (DWI) with quantitative apparent diffusion coefficient (ADC) mapping in the diagnosis of maxillary diseases.
We evaluated 146 cases of maxillary diseases (32 malignant tumors, 11 benign tumors, 28 maxillary cysts, 60 cases of maxillary sinusitis, and 15 maxillary sinus retention cysts) that had been examined using magnetic resonance imaging. The DWI sequence was obtained with b values of 0 and 800 s/mm and ADC values were calculated. We used one-way analysis of variance and the Tukey honestly significant difference test to identify differences within and between the types of diseases.
Mean ADC values for malignant tumors (1.07 × 10 mm s) were significantly lower than ADCs for benign tumors (1.85 × 10 mm s), maxillary cysts (1.77 × 10 mm s), maxillary sinusitis (2.34 × 10 mm s), and maxillary sinus retention cysts (2.52 × 10 mm s), with P < 0.001. Mean ADC differed significantly between all disease types except between maxillary sinusitis and maxillary sinus retention cysts. ADC values also significantly differed between specific lesions within the malignant tumor and maxillary cyst groups.
The use of ADC values can be useful in the differential diagnosis of malignant maxillary diseases, benign lesions, cysts, and inflammatory and reactive conditions.
我们研究了使用扩散加权成像（DWI）结合定量表观扩散系数（ADC）图对上颌疾病进行诊断的效果。
我们评估了 146 例上颌疾病患者（32 例恶性肿瘤、11 例良性肿瘤、28 例上颌囊肿、60 例上颌窦炎和 15 例上颌窦潴留囊肿）的磁共振成像检查结果。使用 b 值为 0 和 800 s/mm 的 DWI 序列获得 ADC 值。我们使用单因素方差分析和 Tukey Honestly Significant Difference 检验来识别疾病类型内和类型间的差异。
恶性肿瘤的平均 ADC 值（1.07×10mm/s）明显低于良性肿瘤（1.85×10mm/s）、上颌囊肿（1.77×10mm/s）、上颌窦炎（2.34×10mm/s）和上颌窦潴留囊肿（2.52×10mm/s），P<0.001。除上颌窦炎和上颌窦潴留囊肿外，所有疾病类型的平均 ADC 值均存在显著差异。恶性肿瘤和上颌囊肿组内的特定病变之间的 ADC 值也存在显著差异。
ADC 值的使用可有助于鉴别诊断恶性上颌疾病、良性病变、囊肿以及炎症和反应性疾病。
