Văduva Constantin Cristian, Constantinescu Carmen, Ţenovici Mihaela, Boldeanu Lidia, Istrate-Ofiţeru Anca Maria
Department of Obstetrics and Gynecology, Department of Microbiology, University of Medicine and Pharmacy of Craiova, Romania;
Rom J Morphol Embryol. 2023 Apr-Jun;64(2):143-150. doi: 10.47162/RJME.64.2.03.
Borderline ovarian tumors (BOTs) are a group of tumors with histological aspects and intermediate biological evolution between benign and malignant tumors, characterized by epithelial proliferation, lack of stromal invasion and nuclear atypia. BOTs account for approximately 10-15% of epithelial ovarian carcinomas. The interest in fertility preservation is very important as most BOTs are diagnosed in patients less than 40 years of age. Since borderline tumors occur in young, fertile women, the therapeutic approach depends on both staging and the need to preserve ovarian function and fertility. Treatment of BOT is primarily surgical, but recently fertility-preserving surgery has become more important. If infertility persists, ovarian induction or in vitro fertilization (IVF) may be suggested in selected cases.
卵巢交界性肿瘤（BOTs）是一组在组织学特征和生物学行为上介于良性和恶性肿瘤之间的肿瘤，其特点是上皮细胞增生、无间质浸润和核异型性。BOTs约占上皮性卵巢癌的10%-15%。由于大多数BOTs患者在40岁以下被诊断出来，保留生育功能的意义非常重大。鉴于交界性肿瘤发生于年轻的育龄女性，治疗方法取决于分期以及保留卵巢功能和生育能力的需求。BOT的治疗主要是手术，但近年来保留生育功能的手术变得更为重要。如果不孕问题持续存在，在特定情况下可考虑卵巢刺激或体外受精（IVF）。
