Department of Medical Laboratory, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Department of Medical Laboratory, Shiyan Hospital of Integrated Traditional and Western Medicine, Shiyan, China.
Front Cell Infect Microbiol. 2023 Jul 14;13:1208473. doi: 10.3389/fcimb.2023.1208473. eCollection 2023.
() is a Gram-negative bacterium initially isolated from in India. has been characterized with low pathogenicity, and no human infections caused by this organism have been reported yet. We report the first case of urinary tract infection caused by in a 73-year-old man after bladder cancer surgery.
The bacterial isolate gained from urine was named UI705 and identified as by MALDI-TOF mass spectrometry. The genome sequencing and analysis were performed to further characterize the pathogenesis of the clinical isolate.
To the best of our knowledge, this is the first report of human infection caused by in China. The draft genome sequence of UI705 provides a fundamental resource for subsequent investigation of its virulence factors, antibiotic resistance, host-pathogen interactions, and comparative genomics of genus .
（）是一种革兰氏阴性菌，最初从印度的（）中分离出来。该菌具有低致病性，尚未有由该病原体引起的人类感染报告。我们报告了首例膀胱癌手术后由（）引起的尿路 73 岁男性感染病例。
从尿液中分离出的细菌命名为 UI705，通过 MALDI-TOF 质谱鉴定为（）。对基因组测序和分析进一步对临床分离株的发病机制进行了表征。
据我们所知，这是在中国首次报告由（）引起的人类感染。UI705 的基因组草图序列为后续研究其毒力因子、抗生素耐药性、宿主-病原体相互作用以及属的比较基因组学提供了基本资源。
