Assery Nasser M, Jurado Carlos A, Assery Mansour K, Afrashtehfar Kelvin I
Department of Periodontology, Eastman Institute for Oral Health, University of Rochester, Rochester, NY 14642, USA.
Department of Prosthodontics, School of Dentistry, Iowa University, Iowa City, IA 52242, USA.
Saudi Dent J. 2023 Jul;35(5):443-450. doi: 10.1016/j.sdentj.2023.04.005. Epub 2023 May 7.
Peri-implantitis is an inflammatory condition induced by bacterial biofilm that affects the soft and hard tissues surrounding dental implants, compromising the success of implant therapy. Recent studies have highlighted the potential links between peri-implant health and systemic inflammation, including uncontrolled diabetes mellitus, psychological stress, cardiovascular disease, obesity, and infectious diseases such as COVID-19. As an inflammatory disease, peri-implantitis may trigger systemic inflammation by elevating circulating levels of pro-inflammatory cytokines, which could have unknown impacts on overall health. While the relationship between periodontal health and systemic conditions is better understood, the association between peri-implant disease and systemic inflammation remains unclear. Therefore, this comprehensive review aims to summarize the most recent evidence on the relationship between peri-implantitis and systemic inflammation, focusing on biological complications, microbiology, and biomarkers. This review aims to enhance our understanding of the links between peri-implantitis and systemic inflammation and promote further research in this field by discussing the latest insights and clinical implications.
种植体周围炎是一种由细菌生物膜引起的炎症性疾病，会影响牙种植体周围的软组织和硬组织，损害种植治疗的成功率。最近的研究强调了种植体周围健康与全身炎症之间的潜在联系，包括未控制的糖尿病、心理压力、心血管疾病、肥胖以及诸如 COVID-19 等传染病。作为一种炎症性疾病，种植体周围炎可能通过提高促炎细胞因子的循环水平来引发全身炎症，这可能对整体健康产生未知影响。虽然牙周健康与全身状况之间的关系已得到更好的理解，但种植体周围疾病与全身炎症之间的关联仍不清楚。因此，本综述旨在总结关于种植体周围炎与全身炎症之间关系的最新证据，重点关注生物学并发症、微生物学和生物标志物。本综述旨在通过讨论最新见解和临床意义，加深我们对种植体周围炎与全身炎症之间联系的理解，并促进该领域的进一步研究。
