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在印度尼西亚偏远地区使用“智能眼相机”进行泪膜破裂时间检查的观察者间可靠性

Interobserver Reliability of Tear Break-Up Time Examination Using "Smart Eye Camera" in Indonesian Remote Area.

作者信息

Handayani Ariesanti Tri, Valentina Clara, Suryaningrum I Gusti Ayu Ratna, Megasafitri Putu Dian, Juliari I Gusti Ayu Made, Pramita Ida Ayu Ary, Nakayama Shintaro, Shimizu Eisuke, Triningrat Anak Agung Mas Putrawati

机构信息

Ophthalmology Study Program Faculty of Medicine, Udayana University, Denpasar, Bali, Indonesia.

Department of Ophthalmology, Keio University School of Medicine, Shinjuku, Tokyo, Japan.

出版信息

Clin Ophthalmol. 2023 Jul 24;17:2097-2107. doi: 10.2147/OPTH.S412233. eCollection 2023.

Abstract

INTRODUCTION

Dry eye disease (DED) is a multifactorial disease of tears and ocular surface that results in symptoms of discomfort, visual disturbance, and tear film instability leading to decrease of vision, productivity and quality of life, and blindness. DED diagnosis remains difficult and underdiagnosed regarding inconsistency between subjective symptoms and clinical findings. Tear break-up time (TBUT) is an objective indicator of tear film stability in diagnostic DED. A novel smartphone attachment, namely SEC (smart eye camera), could mimic conventional slit lamp to assess TBUT and beneficial in facilitating DED diagnosis. Reliability between a non and an ophthalmologist in TBUT assessment and DED diagnosis is observed in this study.

PURPOSE

To determine interobserver reliability of TBUT measurement for diagnosing DED using SEC.

DESIGN

This a cross-sectional analytic study involving 99 participants (198 eyes) aged 40 years who visited Pratama Gema Santi Hospital, Nusa Penida, from September 2nd to 4th, 2022, with consecutive sampling technique.

METHODS

Fluoresceined eyes were filmed using the SEC device and apps, continued by masked ophthalmologist and resident assessing TBUT based on the video. The primary outcome is interobserver reliability for TBUT measurement and DED diagnosis.

RESULTS

The mean age of participants was 55.22±9.78 years, 48.5% male and 51.5% female. The reliability of interobserver in assessing DED based on TBUT test is 0.78 (95% CI=0.31-1.26, -value=0.001), and interobserver reliability in diagnosing DED based on OSDI and TBUT showed good agreement (weighted kappa=0.71). Good interobserver reliability underscores that non-ophthalmologists can diagnose DED based on TBUT video using SEC.

CONCLUSION

SEC video has good interobserver reliability to assess TBUT for DED diagnosis. SEC can be used as one of the methods in assessing DED in limited health care facilities. The high reliability of interobserver assessment indicates that DED diagnosis using video taken with SEC may be useful for telemedicine evaluation in remote areas.

摘要

引言

干眼疾病(DED)是一种累及泪液和眼表的多因素疾病,会导致不适症状、视觉障碍以及泪膜不稳定,进而导致视力下降、工作效率降低、生活质量下降甚至失明。由于主观症状与临床检查结果不一致,DED的诊断仍然困难且存在漏诊情况。泪膜破裂时间(TBUT)是诊断DED时泪膜稳定性的客观指标。一种新型智能手机附件,即SEC(智能眼相机),可以模拟传统裂隙灯来评估TBUT,有助于促进DED的诊断。本研究观察了非眼科医生与眼科医生在TBUT评估和DED诊断方面的可靠性。

目的

确定使用SEC诊断DED时TBUT测量的观察者间可靠性。

设计

这是一项横断面分析研究,采用连续抽样技术,纳入了2022年9月2日至4日访问努沙佩尼达普拉塔马宝石桑蒂医院的99名40岁参与者(198只眼)。

方法

使用SEC设备和应用程序拍摄滴入荧光素后的眼睛,随后由掩蔽的眼科医生和住院医生根据视频评估TBUT。主要结果是TBUT测量和DED诊断的观察者间可靠性。

结果

参与者的平均年龄为55.22±9.78岁,男性占48.5%,女性占51.5%。基于TBUT测试评估DED时观察者间的可靠性为0.78(95%CI=0.31-1.26,P值=0.001),基于OSDI和TBUT诊断DED时观察者间可靠性显示出良好的一致性(加权kappa=0.71)。良好的观察者间可靠性强调非眼科医生可以使用SEC根据TBUT视频诊断DED。

结论

SEC视频在评估TBUT用于DED诊断方面具有良好的观察者间可靠性。SEC可作为有限医疗保健机构中评估DED的方法之一。观察者间评估的高可靠性表明,使用SEC拍摄的视频进行DED诊断可能对偏远地区的远程医疗评估有用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32e7/10378626/55e6237667ac/OPTH-17-2097-g0001.jpg

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