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含有高负载量紫檀芪的高浓缩乳液。

Highly Concentrated Emulsions Containing High Loads of Pterostilbene.

作者信息

Kaade Wael, Rubio Sara, Bogas-Droy Achille, de Villedon Valentine, Laurichesse Eric, Schmitt Veronique

机构信息

Centre de Recherche Paul Pascal, Université Bordeaux 1, CNRS, Avenue du Dr Albert Schweitzer, 33600 Pessac, France.

出版信息

ACS Omega. 2023 Jul 12;8(29):25951-25959. doi: 10.1021/acsomega.3c01861. eCollection 2023 Jul 25.

DOI:10.1021/acsomega.3c01861
PMID:37521615
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10372941/
Abstract

Pterostilbene is a highly researched molecule due to its bioactivity. However, its hydrophobicity limits its application. For this reason, researchers have sought to encapsulate pterostilbene (namely, in oil-in-water emulsion) to increase its availability. Studies are lacking when it comes to the effects of pterostilbene and its concentration at the oil/water interface. This paper discusses the effects of oil types, storage temperature, and pterostilbene concentration on the stability of the emulsions, as well as the interactions between encapsulated pterostilbene and the oil and water phases. Results showed that pterostilbene is present at the oil/water interface, affecting the interfacial tension and consequently the droplet size. It was also shown that encapsulation efficiency is affected by the storage temperature and oil type. Finally, it was proven that, according to oil types and storage temperature, the stability of pterostilbene to light is affected.

摘要

由于其生物活性,紫檀芪是一种经过大量研究的分子。然而,其疏水性限制了它的应用。因此,研究人员试图将紫檀芪封装起来(即在水包油乳液中)以提高其利用率。关于紫檀芪及其在油/水界面处的浓度的影响,目前还缺乏相关研究。本文讨论了油的类型、储存温度和紫檀芪浓度对乳液稳定性的影响,以及被封装的紫檀芪与油相和水相之间的相互作用。结果表明,紫檀芪存在于油/水界面,影响界面张力,进而影响液滴大小。研究还表明,封装效率受储存温度和油的类型影响。最后,经证实,根据油的类型和储存温度,紫檀芪对光的稳定性会受到影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9680/10372941/d01203a77345/ao3c01861_0010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9680/10372941/6871f08ba91c/ao3c01861_0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9680/10372941/693c69484f82/ao3c01861_0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9680/10372941/9b6b55eaa112/ao3c01861_0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9680/10372941/3319c761b2da/ao3c01861_0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9680/10372941/05afea34cd9e/ao3c01861_0006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9680/10372941/474da78cf448/ao3c01861_0007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9680/10372941/21fe86f80c41/ao3c01861_0008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9680/10372941/d2172721e5c7/ao3c01861_0009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9680/10372941/d01203a77345/ao3c01861_0010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9680/10372941/6871f08ba91c/ao3c01861_0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9680/10372941/693c69484f82/ao3c01861_0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9680/10372941/9b6b55eaa112/ao3c01861_0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9680/10372941/3319c761b2da/ao3c01861_0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9680/10372941/05afea34cd9e/ao3c01861_0006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9680/10372941/474da78cf448/ao3c01861_0007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9680/10372941/21fe86f80c41/ao3c01861_0008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9680/10372941/d2172721e5c7/ao3c01861_0009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9680/10372941/d01203a77345/ao3c01861_0010.jpg

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Development and validation of a specific-stability indicating liquid chromatography method for quantitative analysis of pterostilbene: application in food and pharmaceutical products.用于白藜芦醇定量分析的特定稳定性指示液相色谱法的开发与验证:在食品和药品中的应用
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