益生菌在预防和治疗新型冠状病毒肺炎中的潜在应用。
The potential application of probiotics for the prevention and treatment of COVID-19.
作者信息
Elekhnawy Engy, Negm Walaa A
机构信息
Pharmaceutical Microbiology Department, Faculty of Pharmacy, Tanta University, El-Geish Street, Medical Campus, Tanta, 31111 Egypt.
Pharmacognosy Department, Faculty of Pharmacy, Tanta University, Tanta, Egypt.
出版信息
Egypt J Med Hum Genet. 2022;23(1):36. doi: 10.1186/s43042-022-00252-6. Epub 2022 Mar 25.
BACKGROUND
Given the severe infection, poor prognosis, and the low number of available effective drugs, potential prevention and treatment strategies for COVID-19 need to be urgently developed.
MAIN BODY
Herein, we present and discuss the possible protective and therapeutic mechanisms of human microbiota and probiotics based on the previous and recent findings. Microbiota and probiotics consist of mixed cultures of living microorganisms that can positively affect human health through their antiviral, antibacterial, anti-inflammatory, and immunomodulatory effect. In the current study, we address the promising advantages of microbiota and probiotics in decreasing the risk of COVID-19.
CONCLUSIONS
Thus, we recommend further studies be conducted for assessing and evaluating the capability of these microbes in the battle against COVID-19.
背景
鉴于新冠病毒感染严重、预后不佳且可用的有效药物数量有限，亟需制定针对2019冠状病毒病（COVID-19）的潜在预防和治疗策略。
主体
在此，我们根据既往和最新研究结果，介绍并讨论人类微生物群和益生菌可能的保护和治疗机制。微生物群和益生菌由活微生物的混合培养物组成，它们可通过抗病毒、抗菌、抗炎和免疫调节作用对人类健康产生积极影响。在本研究中，我们阐述了微生物群和益生菌在降低COVID-19风险方面的显著优势。
结论
因此，我们建议开展进一步研究，以评估和评价这些微生物在抗击COVID-19中的能力。
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