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在泰国南部,新冠康复患者的长新冠和心理健康状况的流行情况及其相关因素。

Prevalence and factors associated with long COVID and mental health status among recovered COVID-19 patients in southern Thailand.

机构信息

Doctoral Program in Health Sciences, College of Graduate Studies, Walailak University, Nakhon Si Thammarat, Thailand.

Department of Immunology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.

出版信息

PLoS One. 2023 Jul 31;18(7):e0289382. doi: 10.1371/journal.pone.0289382. eCollection 2023.

Abstract

Mental health disorders have become a growing public health concern among individuals recovering from COVID-19. Long COVID, a condition where symptoms persist for an extended period, can predict psychological problems among COVID-19 patients. This study aimed to investigate the prevalence of long COVID and mental health status among Thai adults who had recovered from COVID-19, identify the association between the mental health status and long COVID symptoms, and investigate the risk factors associated with the correlation between long COVID and mental health outcomes. A cross-sectional study was conducted among 939 randomly selected participants in Nakhon Si Thammarat province, southern Thailand. The Depression, Anxiety, and Stress Scale-21 was used to investigate mental health symptoms, and a checklist comprised of thirteen common symptoms was used to identify the long COVID among participants. Logistic regression models were used to investigate the risk factors associated with mental health status and long COVID symptoms among participants. Among the 939 participants, 104 (11.1%) had depression, 179 (19.1%) had anxiety, and 42 (4.8%) were stressed. A total of 745 participants (79.3%) reported experiencing at least one symptom of long COVID, with fatigue (72.9%, SE±0.02), cough (66.0%, SE±0.02), and muscle pain (54.1%, SE±0.02) being the most frequently reported symptoms. All long COVID symptoms were significantly associated with mental health status. Shortness of breath, fatigue, and chest tightness were the highest risk factors for mental health status among COVID-19 patients. The final multivariable model indicated that female patients (OR = 1.89), medical history (OR = 1.92), and monthly income lower than 5,000 Thai baht (OR = 2.09) were associated with developing long COVID symptoms and mental health status (all p<0.01). This study provides valuable insights into the potential long-term effects of COVID-19 on mental health and enhances understanding of the mechanisms underlying the condition for predicting the occurrence of mental health issues in Thai COVID-19 patients.

摘要

心理健康障碍已成为 COVID-19 康复者日益关注的公共卫生问题。长新冠是指症状持续较长时间的一种情况,它可以预测 COVID-19 患者的心理问题。本研究旨在调查泰国 COVID-19 康复者中长新冠和心理健康状况的流行情况,确定心理健康状况与长新冠症状之间的关联,并调查与长新冠和心理健康结果相关的关联的危险因素。在泰国南部那空是贪玛叻府,对 939 名随机选择的参与者进行了横断面研究。使用抑郁、焦虑和压力量表 21 调查心理健康症状,使用包含 13 种常见症状的检查表来识别参与者中的长新冠。使用逻辑回归模型调查与参与者心理健康状况和长新冠症状相关的危险因素。在 939 名参与者中,104 人(11.1%)患有抑郁症,179 人(19.1%)患有焦虑症,42 人(4.8%)感到压力。共有 745 名参与者(79.3%)报告至少有一种长新冠症状,其中疲劳(72.9%,SE±0.02)、咳嗽(66.0%,SE±0.02)和肌肉疼痛(54.1%,SE±0.02)是最常报告的症状。所有长新冠症状均与心理健康状况显著相关。呼吸急促、疲劳和胸闷是 COVID-19 患者心理健康状况的最高危险因素。最终的多变量模型表明,女性患者(OR=1.89)、有病史(OR=1.92)和月收入低于 5000 泰铢(OR=2.09)与长新冠症状和心理健康状况相关(均 P<0.01)。本研究提供了有关 COVID-19 对心理健康的潜在长期影响的有价值的见解,并增强了对预测泰国 COVID-19 患者心理健康问题发生机制的理解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/156d/10389739/eb24820d1496/pone.0289382.g001.jpg

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