Laboratorio Referencial de Salud de Chachapoyas, Dirección Regional de Salud Amazonas, Chachapoyas, Perú.
Instituto de Enfermedades Tropicales, Universidad Nacional Toribio Rodríguez de Mendoza de Amazonas, Chachapoyas, Perú.
Am J Trop Med Hyg. 2023 Jul 31;109(3):523-526. doi: 10.4269/ajtmh.22-0739. Print 2023 Sep 6.
Peru was severely affected by COVID-19 with a fatality rate that reached up to 6%. In this study, the relationship between SARS-CoV-2 variants and COVID-19 disease outcome in Amazonas, a region of northeastern Peru, was evaluated. The variants were determined by genomic sequencing, and clinical-epidemiological data were collected from 590 patients between April 2021 and February 2022. There was no association between mortality and hospitalization with any of the variants, but we did find that Omicron is more likely to infect vaccinated and nonvaccinated people. A significant association was also found between unvaccinated patients and hospitalization. Interestingly, in the indigenous population, there were fewer hospitalizations than in the general population. In conclusion, SARS-CoV-2 variants were not associated with the disease outcome in the Amazonas region, and indigenous population were found to be less vulnerable to severe COVID-19 illness.
秘鲁受到 COVID-19 的严重影响，死亡率高达 6%。在这项研究中，评估了亚马逊地区（秘鲁东北部的一个地区）的 SARS-CoV-2 变体与 COVID-19 疾病结局之间的关系。通过基因组测序确定了变体，并且从 2021 年 4 月至 2022 年 2 月间收集了 590 名患者的临床流行病学数据。死亡率和住院率与任何变体均无关联，但我们确实发现，奥密克戎更可能感染接种和未接种疫苗的人。未接种疫苗的患者与住院治疗之间也存在显著关联。有趣的是，在土著人群中，住院人数比一般人群少。总之，在亚马逊地区，SARS-CoV-2 变体与疾病结局无关，并且土著人群似乎不易受到严重 COVID-19 疾病的影响。
