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印度南部产前妇女妊娠中晚期使用胎儿肾长超声估计孕周:一项横断面研究

Ultrasonographic Estimation of the Gestational Age Using the Fetal Kidney Length in the Second and Third Trimesters of Pregnancy Among South Indian Antenatal Women: A Cross-Sectional Study.

作者信息

M Mahima Sophia, Maria Francis Yuvaraj, Karunakaran Balaji, G Sankara Narayanan

机构信息

Anatomy, Panimalar Medical College Hospital & Research Institute, Chennai, IND.

Anatomy, Saveetha Medical College, Saveetha Institute of Medical and Technical Sciences, Chennai, IND.

出版信息

Cureus. 2023 Jun 30;15(6):e41172. doi: 10.7759/cureus.41172. eCollection 2023 Jun.

Abstract

Background and Objective Accurately estimating the age of the fetus is crucial to prevent morbidity and mortality for both the fetus and mother during the perinatal period. Additionally, it enables early intervention in cases of complicated pregnancies. Multiple parameters are used for the estimation of fetal gestational age (FGA) and the expected date of delivery (EDD), but no single parameter is found to be accurate and standard. This study aims to analyze the fetal kidney length (FKL) as a means to estimate gestational age and investigate the growth pattern of the fetal kidney during the early and late weeks of gestation. Furthermore, it seeks to establish correlations between FKL and gold standard parameters from the 18th week to the 38th week of gestation. Methodology This cross-sectional research was carried out after obtaining proper institutional ethical clearance. The pregnant women who came to the gynecology outpatient department (OPD) between 18 and 38 weeks were included in this study after obtaining informed consent. The fetal biometry was measured using the ultrasonographic transducer (3-5 MHz). Results The mean FKL exhibited a consistent increase throughout the entire pregnancy, ranging from 16.50 ± 2.10 to 39.20 ± 3.10 mm. The rate of increase in FKL was significant between the early weeks (18-24) of pregnancy, with insignificant growth in other weeks of gestation. The growth of the fetal kidney (length) exhibited a gradual increase from the early weeks to the late weeks of pregnancy, with a consistent growth rate of approximately 1mm per week from 18 to 35 weeks. However, in the final three weeks of pregnancy (36th, 37th, and 38th weeks), the FKL measurements were recorded as 37.90 ± 3.90, 38.90 ± 3.10, and 40.20 ± 3.10 mm, respectively. A positive correlation was noted between the FKL with all standard parameters such as biparietal diameter (BPD), femur length (FL), head circumference (HC), and abdominal circumference (AC). Conclusions This study concluded that incorporating FKL alongside standard fetal biometric parameters such as BPD, FL, HC, and AC enhanced the accuracy of calculating FGA and EDD during the early second trimester. Furthermore, it proved beneficial in diagnosing fetal anomalies during early pregnancies.

摘要

背景与目的 准确估计胎儿年龄对于预防围产期胎儿和母亲的发病及死亡至关重要。此外,它还能在复杂妊娠情况下实现早期干预。多种参数用于估计胎儿孕周(FGA)和预产期(EDD),但未发现单一参数准确且标准。本研究旨在分析胎儿肾长(FKL)作为估计孕周的一种方法,并研究妊娠早期和晚期胎儿肾脏的生长模式。此外,它试图在妊娠第18周 至第38周建立FKL与金标准参数之间的相关性。方法 本横断面研究在获得适当的机构伦理批准后进行。在获得知情同意后,将妊娠18至38周前来妇科门诊(OPD)的孕妇纳入本研究。使用超声换能器(3 - 5MHz)测量胎儿生物测量值。结果 整个孕期平均FKL持续增加,范围从16.50±2.10至39.20±3.10mm。妊娠早期(18 - 24周)FKL增加速率显著,妊娠其他周增长不显著。胎儿肾脏(长度)从妊娠早期到晚期逐渐增大,18至35周每周一致的增长率约为1mm。然而,在妊娠最后三周(第36、37和38周),FKL测量值分别记录为37.90±3.90、38.90±3.10和40.20±3.10mm。FKL与所有标准参数如双顶径(BPD)、股骨长度(FL)、头围(HC)和腹围(AC)之间存在正相关。结论 本研究得出结论,将FKL与标准胎儿生物测量参数如BPD、FL、HC和AC相结合,可提高孕中期早期计算FGA和EDD的准确性。此外,它在早期妊娠诊断胎儿异常方面被证明是有益的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd25/10387180/a1f0144a7b10/cureus-0015-00000041172-i01.jpg

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