Liu Chen-Xu, Yin Si-Yong, Zhao Fangnuo, Yang Hui, Feng Zuolijun, Gu Qing, You Shu-Li
New Cornerstone Science Laboratory, State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 345 Lingling Lu, Shanghai 200032, P. R. China.
Chem Rev. 2023 Aug 23;123(16):10079-10134. doi: 10.1021/acs.chemrev.3c00149. Epub 2023 Aug 1.
This review summarizes the advancements in rhodium-catalyzed asymmetric C-H functionalization reactions during the last two decades. Parallel to the rapidly developed palladium catalysis, rhodium catalysis has attracted extensive attention because of its unique reactivity and selectivity in asymmetric C-H functionalization reactions. In recent years, Rh-catalyzed asymmetric C-H functionalization reactions have been significantly developed in many respects, including catalyst design, reaction development, mechanistic investigation, and application in the synthesis of complex functional molecules. This review presents an explicit outline of catalysts and ligands, mechanism, the scope of coupling reagents, and applications.
本综述总结了过去二十年来铑催化的不对称C-H官能化反应的进展。与迅速发展的钯催化并行，铑催化因其在不对称C-H官能化反应中独特的反应性和选择性而受到广泛关注。近年来，铑催化的不对称C-H官能化反应在许多方面都有了显著发展，包括催化剂设计、反应开发、机理研究以及在复杂功能分子合成中的应用。本综述给出了催化剂和配体、机理、偶联试剂范围及应用的明确概述。
