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虚拟现实暴露与放松训练在音乐表演焦虑中的应用:一项随机对照研究。

The application of virtual reality exposure versus relaxation training in music performance anxiety: a randomized controlled study.

机构信息

Department of Psychiatry, Psychosomatics, and Psychotherapy, Center for Mental Health, University Hospital Würzburg, Würzburg, Germany.

University of Music Würzburg, Würzburg, Germany.

出版信息

BMC Psychiatry. 2023 Aug 1;23(1):555. doi: 10.1186/s12888-023-05040-z.

Abstract

BACKGROUND

Performance anxiety is the most frequently reported anxiety disorder among professional musicians. Typical symptoms are - on a physical level - the consequences of an increase in sympathetic tone with cardiac stress, such as acceleration of heartbeat, increase in blood pressure, increased respiratory rate and tremor up to nausea or flush reactions. These symptoms can cause emotional distress, a reduced musical and artistical performance up to an impaired functioning. While anxiety disorders are preferably treated using cognitive-behavioral therapy with exposure, this approach is rather difficult for treating music performance anxiety since the presence of a public or professional jury is required and not easily available. The use of virtual reality (VR) could therefore display an alternative. So far, no therapy studies on music performance anxiety applying virtual reality exposure therapy have investigated the therapy outcome including cardiovascular changes as outcome parameters.

METHODS

This mono-center, prospective, randomized and controlled clinical trial has a pre-post design with a follow-up period of 6 months. 46 professional and semi-professional musicians will be recruited and allocated randomly to an VR exposure group or a control group receiving progressive muscle relaxation training. Both groups will be treated over 4 single sessions. Music performance anxiety will be diagnosed based on a clinical interview using ICD-10 and DSM-5 criteria for specific phobia or social anxiety. A behavioral assessment test is conducted three times (pre, post, follow-up) in VR through an audition in a concert hall. Primary outcomes are the changes in music performance anxiety measured by the German Bühnenangstfragebogen and the cardiovascular reactivity reflected by heart rate variability (HRV). Secondary outcomes are changes in blood pressure, stress parameters such as cortisol in the blood and saliva, neuropeptides, and DNA-methylation.

DISCUSSION

The trial investigates the effect of VR exposure in musicians with performance anxiety compared to a relaxation technique on anxiety symptoms and corresponding cardiovascular parameters. We expect a reduction of anxiety but also a consecutive improvement of HRV with cardiovascular protective effects.

TRIAL REGISTRATION

This study was registered on clinicaltrials.gov. (ClinicalTrials.gov Number: NCT05735860).

摘要

背景

表现焦虑是专业音乐家中最常报告的焦虑症。典型症状是——在身体层面上——交感神经张力增加的后果,如心跳加速、血压升高、呼吸频率加快以及震颤至恶心或潮红反应。这些症状会引起情绪困扰、音乐和艺术表现下降,甚至功能受损。虽然焦虑症最好通过认知行为疗法结合暴露疗法进行治疗,但由于需要存在观众或专业评审团,这种方法对于治疗音乐表演焦虑症来说比较困难,而且不容易获得。因此,虚拟现实 (VR) 的应用可能是一种替代方法。迄今为止,尚无使用虚拟现实暴露疗法治疗音乐表演焦虑症的治疗研究调查过包括心血管变化在内的治疗结果作为疗效参数。

方法

这项单中心、前瞻性、随机对照临床试验采用前后设计,随访期为 6 个月。将招募 46 名专业和半专业音乐家,并随机分配到 VR 暴露组或接受渐进性肌肉松弛训练的对照组。两组均接受 4 次单一疗程治疗。根据 ICD-10 和 DSM-5 特定恐惧症或社交焦虑症标准,使用临床访谈对音乐表演焦虑症进行诊断。通过在音乐厅进行的试演,在 VR 中进行三次行为评估测试(治疗前、治疗后和随访)。主要结局是使用德国 Bühnenangstfragebogen 测量的音乐表演焦虑症变化和心率变异性 (HRV) 反映的心血管反应性。次要结局是血压、血液和唾液中的皮质醇等应激参数、神经肽和 DNA 甲基化的变化。

讨论

该试验比较了 VR 暴露治疗与放松技术对有表演焦虑症的音乐家的焦虑症状和相应心血管参数的影响。我们预计焦虑症会减轻,同时 HRV 也会随之改善,具有心血管保护作用。

试验注册

本研究在 clinicaltrials.gov 上注册。(临床试验.gov 编号:NCT05735860)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a7a/10394851/a977dfeb01b5/12888_2023_5040_Fig1_HTML.jpg

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