Tian Ting, Zhang Jingwen, Lin Shiyun, Jiang Yukang, Tan Jianbin, Li Zhongfei, Wang Xueqin
School of Mathematics, Sun Yat-sen University, Guangzhou, People's Republic of China.
Center for Statistical Science, Peking University, Beijing, People's Republic of China.
J Appl Stat. 2021 Mar 9;50(11-12):2547-2560. doi: 10.1080/02664763.2021.1895089. eCollection 2023.
Since February 2020, COVID-19 has spread rapidly to more than 200 countries in the world. During the pandemic, local governments in China have implemented different interventions to efficiently control the spread of the epidemic. Characterizing transmission of COVID-19 under some typical interventions is essential to help countries develop appropriate interventions. Based on the pre-symptomatic transmission patterns of COVID-19, we established a novel compartmental model: Susceptible-Infectious-Confirmed-Removed (SICR) model, which allowed the effective reproduction number to change over time, thus the effects of policies could be reasonably estimated. Using the epidemic data of Wuhan, Wenzhou, and Shenzhen, we migrated the corresponding estimated policy modes to South Korea, Italy, and the United States and simulated the potential outcomes for these countries when they adopted similar policy strategies to China. We found that the mild interventions implemented in Shenzhen were effective in controlling the epidemic in the early stage, while more stringent policies which were implemented in Wuhan and Wenzhou were necessary if the epidemic became severe and needed to be controlled in a short time.
自2020年2月以来,新冠病毒已迅速传播至全球200多个国家。疫情期间,中国地方政府实施了不同的干预措施以有效控制疫情传播。明确新冠病毒在一些典型干预措施下的传播特征,对于帮助各国制定适当的干预措施至关重要。基于新冠病毒的症状前传播模式,我们建立了一个新的 compartmental 模型:易感-感染-确诊-康复(SICR)模型,该模型允许有效繁殖数随时间变化,从而能够合理估计政策的效果。利用武汉、温州和深圳的疫情数据,我们将相应的估计政策模式迁移至韩国、意大利和美国,并模拟了这些国家采取与中国类似政策策略时的潜在结果。我们发现,深圳实施的轻度干预措施在疫情早期对控制疫情有效,而武汉和温州实施的更严格政策在疫情变得严重且需要在短时间内控制时是必要的。