State Key Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.
Pharmacy department, Sichuan Nursing Vocational College, Chengdu 610100, China.
Food Funct. 2023 Aug 29;14(17):7738-7759. doi: 10.1039/d3fo01671d.
The fruit of Linn., which mainly grows in tropical and subtropical regions, is well-known for its medicine and food homology properties. It has a distinctive flavor, great nutritional content, and potent antioxidant, anti-inflammatory, anti-cancer and immunoregulatory effects. According to an increasing amount of scientific and clinical evidence, this fruit shows significant potential for application and development in the field of oral health management. Through the supplementation of vitamins, superoxide dismutase (SOD) and other nutrients reduce virulence expression of various oral pathogens, prevent tissue and mucosal damage caused by oxidative stress, . fruit can promote saliva secretion, regulate the balance of the oral microecology, prevent and treat oral cancer early, promote alveolar bone remodeling and aid mucosal wound healing. Thus, it plays a specific role in the prevention and treatment of common oral disorders, producing surprising results. For instance, enhancing the effectiveness of scaling and root planing in the treatment of periodontitis, relieving mucosal inflammation caused by radiotherapy for oral cancer, and regulating the blood glucose metabolism to alleviate oral discomfort. Herein, we systematically review the latest research on the use of fruit in the management of oral health and examine the challenges and future research directions based on its chemical composition and characteristics.
林奈的果实,主要生长在热带和亚热带地区,以其药食同源的特性而闻名。它具有独特的风味、丰富的营养成分和强大的抗氧化、抗炎、抗癌和免疫调节作用。越来越多的科学和临床证据表明,这种水果在口腔健康管理领域具有显著的应用和发展潜力。通过补充维生素、超氧化物歧化酶(SOD)等营养物质,可以降低各种口腔病原体的毒力表达,防止氧化应激引起的组织和黏膜损伤。这种水果可以促进唾液分泌,调节口腔微生态平衡,预防和早期治疗口腔癌,促进牙槽骨重塑,辅助黏膜伤口愈合。因此,它在预防和治疗常见的口腔疾病方面发挥着特定的作用,取得了令人惊讶的效果。例如,增强牙周炎治疗中洁治和根面平整的效果,缓解口腔癌放疗引起的黏膜炎症,以及调节血糖代谢以减轻口腔不适。在此,我们系统地综述了林奈果实用于口腔健康管理的最新研究,并根据其化学成分和特性,探讨了挑战和未来的研究方向。