Baram D V, Asaulenko Z P, Spiridonov I N, Krivolapov Yu A
Russian Research Institute of Hematology and Transfusiology, St. Petersburg, Russia.
North-Western State Medical University named after I.I. Mechnikov, St. Petersburg, Russia.
Arkh Patol. 2023;85(4):24-31. doi: 10.17116/patol20238504124.
The paper discusses changes in the structure of the classification, criteria for the diagnosis of lymphoid neoplasms in the 5th edition of the WHO Classification of Tumors of Hematopoietic and Lymphoid Tissues (2022). Changes are presented regarding new nosological units, renaming and abolition of some previously existing ones. The importance of molecular genetic studies in the isolation of many lymphomas and the need to apply these studies in everyday clinical practice are emphasized. Lymphoid precancerous processes and lymphoid proliferations introduced into the Classification for the first time are considered.
本文讨论了《世界卫生组织造血与淋巴组织肿瘤分类》第5版(2022年)中淋巴肿瘤分类结构的变化、诊断标准。介绍了新的疾病分类单元、一些先前存在的分类单元的重新命名和废除情况。强调了分子遗传学研究在许多淋巴瘤鉴别诊断中的重要性以及在日常临床实践中应用这些研究的必要性。还讨论了首次纳入该分类的淋巴癌前病变过程和淋巴增生性病变。