Child and Adolescent Studies, Utrecht University, Utrecht, The Netherlands.
Department of Clinical, Neuro and Developmental Psychology, Vrije Universiteit Amsterdam, Amsterdam Public Health Research Institute, Amsterdam, The Netherlands.
J Autism Dev Disord. 2024 Sep;54(9):3492-3503. doi: 10.1007/s10803-023-06069-5. Epub 2023 Aug 2.
The current study evaluated a brief, informant-based autism interview: the Developmental, Dimensional and Diagnostic Interview - Adult Version (3Di-Adult). Feasibility, reliability and validity of the Dutch 3Di-Adult was tested amongst autistic participants (n = 62) and a non-autistic comparison group (n = 30) in the Netherlands. The 3Di-Adult consists of two scales based on DSM-5 criteria: A scale 'Social communication and social interaction' and B scale 'Restricted, repetitive patterns of behavior, interests or activities'. ROC curves were used to determine cut-off scores for the A and the B scale, using an ASD diagnosis made by an independent clinician as the criterion. Mean administration time was 42 min. Internal consistency of the A scale (α = 0.92) and the B scale (α = 0.85) were good. Inter-rater reliability (ICCs = 0.99) and inter-rater agreement (ICCs ≥ 0.90) were promising. The 3Di-Adult showed good sensitivity (80.6%) and specificity (93.3%). Positive and negative predictive value were 96.2% and 70.0% respectively. Comparisons with the Autism-Spectrum Quotient-Short to investigate the convergent validity showed moderate, significant correlations with the 3Di-Adult in the total sample. Males, as compared to females, displayed significantly more autistic features on the 3Di-Adult. No relationship was found of the 3Di-Adult with education level, intelligence and age of the participants or informants. The feasibility and psychometric properties of the Dutch 3Di-Adult are promising, indicating that it can be a time-efficient, valid and reliable tool to use in diagnosing autism in adults according to DSM-5 criteria.
当前的研究评估了一种简短的、基于知情者的自闭症访谈：发展、维度和诊断访谈-成人版（3Di-Adult）。在荷兰，该研究对 62 名自闭症患者和 30 名非自闭症对照组参与者进行了荷兰语 3Di-Adult 的可行性、可靠性和有效性测试。3Di-Adult 由基于 DSM-5 标准的两个量表组成：A 量表“社交沟通和社交互动”和 B 量表“受限、重复的行为、兴趣或活动模式”。使用独立临床医生做出的 ASD 诊断作为标准，ROC 曲线用于确定 A 量表和 B 量表的截断分数。平均管理时间为 42 分钟。A 量表（α=0.92）和 B 量表（α=0.85）的内部一致性良好。评分者间信度（ICC=0.99）和评分者间一致性（ICC≥0.90）都很有前景。3Di-Adult 的灵敏度（80.6%）和特异性（93.3%）都很好。阳性和阴性预测值分别为 96.2%和 70.0%。与自闭症谱系商数量表-短版的比较，以调查其收敛有效性，结果表明在总样本中与 3Di-Adult 有中度显著相关性。与女性相比，男性在 3Di-Adult 上表现出更多的自闭症特征。在参与者或知情者的教育程度、智力和年龄方面，未发现 3Di-Adult 与其有任何关系。荷兰语 3Di-Adult 的可行性和心理测量学特性很有前景，表明它可以成为一种根据 DSM-5 标准诊断成人自闭症的高效、有效和可靠工具。
